Description

1-(3-Fluorophenyl)-4-Methylpiperazine is a versatile fluorinated piperazine derivative, a key building block in advanced organic synthesis. Its value lies in its ability to introduce both a fluorinated aromatic moiety and a substituted piperazine ring, which are crucial pharmacophores in modern drug discovery. This compound is primarily needed by pharmaceutical R&D teams and fine chemical manufacturers engaged in developing new active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and psychiatric therapeutics.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel drug candidates, especially those targeting serotonin and dopamine receptors.
• Agrochemical Research: Used in the development of new pesticides and herbicides, where the fluorine atom enhances biological activity and metabolic stability.
• Ligand Synthesis: Serves as a key component for creating complex ligands used in catalysis and material science.
• Chemical Biology Probes: Employed in the design of molecular probes for studying enzyme function and receptor interactions.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific synthesis projects.

Basic Information

Product Name	1-(3-Fluorophenyl)-4-Methylpiperazine
CAS No.	218940-66-0
Molecular Formula	C11H15FN2
Molecular Weight	194.25 g/mol
Synonyms	1-(3-Fluorophenyl)-4-methylpiperazine; 4-Methyl-1-(3-fluorophenyl)piperazine; 3-Fluoro-N-methyl-N-phenylpiperazine; N-Methyl-N-(3-fluorophenyl)piperazine; 1-(m-Fluorophenyl)-4-methylpiperazine; 218940-66-0; 4-Methyl-1-(3-fluorophenyl)piperazine
EINECS	Contact for details

Quality Control

Our 1-(3-Fluorophenyl)-4-Methylpiperazine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.