Description

2-(((9H-Fluoren-9-Yl)Methoxy)Carbonylamino)-2-Ethylbutanoic Acid is a specialized Fmoc-protected amino acid derivative, a critical building block in modern solid-phase peptide synthesis (SPPS). Its primary value lies in enabling the controlled and efficient assembly of complex peptide chains, which is essential for pharmaceutical research and development. This high-purity intermediate is indispensable for researchers and manufacturers in the pharmaceutical, biotechnology, and life sciences sectors who require reliable, high-quality raw materials for producing therapeutic peptides and peptidomimetics.

Application

• Solid-Phase Peptide Synthesis (SPPS): A key protected amino acid building block for the automated synthesis of custom peptides.
• Pharmaceutical Intermediates: Used in the research and production of active pharmaceutical ingredients (APIs) for peptide-based drugs.
• Bioconjugation and Labeling: Serves as a precursor for creating peptide conjugates used in diagnostics and targeted drug delivery systems.
• Combinatorial Chemistry Libraries: Employed to generate diverse arrays of peptide compounds for high-throughput screening in drug discovery.
• Biochemical Research: Essential for studying protein-protein interactions, enzyme substrates, and receptor ligands.
• Antibiotic and Hormone Synthesis: A critical component in the synthesis of complex natural products and peptide hormones.

Basic Information

Product Name	2-(((9H-Fluoren-9-Yl)Methoxy)Carbonylamino)-2-Ethylbutanoic Acid
CAS No.	218926-46-6
Molecular Formula	C₂₁H₂₃NO₄
Molecular Weight	353.41 g/mol
Synonyms	Fmoc-Aib(2-Et)-OH; Fmoc-2-amino-2-ethylbutyric acid; N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-2-ethyl-2-aminobutanoic acid; 2-Ethyl-2-[[(9H-fluoren-9-ylmethoxy)carbonyl]amino]butanoic acid; Fmoc-2-ethyl-2-aminobutanoic acid; N-Fmoc-2-amino-2-ethylbutanoic acid; 2-(((9H-Fluoren-9-yl)methoxy)carbonylamino)-2-ethylbutanoic acid; Fmoc-α-ethyl-α-aminobutyric acid
EINECS	Contact for details

Quality Control

Our 2-(((9H-Fluoren-9-Yl)Methoxy)Carbonylamino)-2-Ethylbutanoic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high purity and consistent performance for sensitive peptide synthesis applications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This compound is hygroscopic (moisture-sensitive); therefore, containers should be kept sealed and under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation. Handle and store in accordance with good laboratory practices.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Purity (HPLC, Total)	≥99.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Optical Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.