Description

2-Fluoro-5-Formylbenzonitrile is a versatile aromatic nitrile building block characterized by its reactive aldehyde and cyano functional groups. This compound is essential for advanced organic synthesis, enabling the construction of complex molecular architectures through its dual reactivity. It is primarily utilized by researchers and manufacturers in the pharmaceutical and agrochemical industries for the development of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules containing fluorinated aromatic systems.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the fluorine atom enhances biological activity and stability.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands and organocatalysts used in asymmetric synthesis and metal-catalyzed reactions.
• Material Science Research: Employed in the development of organic electronic materials, such as fluorinated polymers and liquid crystals, due to its electron-withdrawing groups.
• Custom Synthesis and Contract Manufacturing: A critical building block for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the global life sciences market.

Basic Information

Product Name	2-Fluoro-5-Formylbenzonitrile
CAS No.	218301-22-5
Molecular Formula	C8H4FNO
Molecular Weight	149.12 g/mol
Synonyms	5-Cyano-2-fluorobenzaldehyde; 2-Fluoro-5-cyanobenzaldehyde; 2-Fluorobenzene-1,4-dicarbonitrile (incorrect but common misnomer); 5-Formyl-2-fluorobenzonitrile; 2-Fluoro-5-formylbenzenecarbonitrile; 218301-22-5; 2-Fluor-5-formylbenzonitril; 2-Fluoro-5-aldehydrobenzonitrile
EINECS	Contact for details

Quality Control

Our 2-Fluoro-5-Formylbenzonitrile is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and FTIR, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed specifications are provided for every shipment, supporting your regulatory and R&D requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). The compound is moisture-sensitive; keep the container tightly sealed under an inert atmosphere for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.