Description

Razaxaban CAS NO 218298-21-6 is a potent, selective, and orally active direct inhibitor of coagulation factor Xa (FXa). This compound is a high-value pharmaceutical intermediate and research chemical critical for the development of next-generation anticoagulant therapies. It is primarily utilized by pharmaceutical R&D teams, contract research organizations (CROs), and academic institutions focused on cardiovascular and thrombosis research.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of advanced anticoagulant drug candidates.
• Biochemical Research: Used as a reference standard and tool compound in studies of the coagulation cascade and FXa inhibition mechanisms.
• Preclinical Development: Essential for pharmacokinetic (PK), pharmacodynamic (PD), and toxicology studies for novel antithrombotic agents.
• Analytical Standard: Serves as a high-purity standard for method development and validation in quality control laboratories.

Basic Information

Product Name	Razaxaban
CAS No.	218298-21-6
Molecular Formula	C23H23FN6O3
Molecular Weight	450.47 g/mol
Synonyms	Razaxaban; BMS-561389; DPC-906; 1-(3-Amidinophenyl)-3-[1-(2-pyridinyl)piperidin-4-yl]methyl-5-[4-(trifluoromethoxy)phenyl]-1H-1,2,4-triazole; 1H-1,2,4-Triazole, 1-[3-(aminoiminomethyl)phenyl]-3-[[1-(2-pyridinyl)-4-piperidinyl]methyl]-5-[4-(trifluoromethoxy)phenyl]-
EINECS	Contact for details

Quality Control

Our Razaxaban is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation (IR, MS), to ensure it meets the stringent requirements for pharmaceutical research. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting compliance with specified standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥98.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.