Description

Pyr-Arg-Pro-Arg-Leu-Ser-His-Lys-Gly-Pro-Met-Pro-Phe-Oh is a synthetic peptide sequence of significant interest in biochemical and pharmaceutical research. This compound matters as a key tool for studying protease interactions, enzyme kinetics, and as a potential precursor or reference standard in therapeutic peptide development. It is primarily needed by research institutions, biotechnology companies, and pharmaceutical developers focused on cardiovascular, metabolic, and inflammatory pathways.

Application

• Biochemical Research: Used as a substrate or inhibitor in enzymatic assays to study the activity and specificity of proteases like thrombin or other serine proteases.
• Pharmaceutical R&D: Serves as a critical reference standard or an intermediate in the development of novel peptide-based therapeutics targeting blood coagulation and related disorders.
• Proteomics & Diagnostics: Employed in mass spectrometry and chromatography as a calibrant or model compound for method development and validation in protein/peptide analysis.
• Academic Studies: Utilized in university and institutional labs for fundamental research into peptide structure-activity relationships and signal transduction mechanisms.

Basic Information

Item	Details
Product Name	Pyr-Arg-Pro-Arg-Leu-Ser-His-Lys-Gly-Pro-Met-Pro-Phe-Oh
CAS No.	217082-60-5
Molecular Formula	C73H119N27O18S
Molecular Weight	1646.9 g/mol
Synonyms	Pyr-RPRL-SH-KG-PM-PF-OH; Pyroglutamyl-Arginyl-Prolyl-Arginyl-Leucyl-Seryl-Histidyl-Lysyl-Glycyl-Prolyl-Methionyl-Prolyl-Phenylalanyl Alcohol; Thrombin Inhibitor Peptide Fragment; Pyr-RPRLSHKGPM-PF-OH; Synthetic Tetradecapeptide; CAS 217082-60-5
EINECS	Contact for details

Quality Control

Our Pyr-Arg-Pro-Arg-Leu-Ser-His-Lys-Gly-Pro-Met-Pro-Phe-Oh is produced under stringent quality management systems. Each batch undergoes comprehensive analytical testing including HPLC for purity, mass spectrometry (MS) for identity confirmation, and amino acid analysis (AAA). Certificates of Analysis (COA) detailing purity, peptide content, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). For long-term storage, it is recommended to store desiccated. Allow the vial to warm to room temperature in a desiccator before opening to minimize moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Peptide Content	≥ 80% (by AAA)
Single Impurity (HPLC)	≤ 1.0%
Water Content (KF)	≤ 5.0%
Acetate Content (HPIC)	≤ 10.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.