Description

Apelin Precursor (61-77) (Human, Bovine, Mouse, Rat) Trifluoroacetate is a high-purity synthetic peptide fragment corresponding to the C-terminal region of the apelin proprotein. This compound serves as a critical research tool for studying the apelin/APJ receptor system, a key signaling pathway involved in cardiovascular function, fluid homeostasis, and metabolic regulation. It is essential for scientists in pharmaceutical R&D, academic biochemistry, and biotechnology sectors conducting receptor-ligand interaction studies, assay development, and preclinical research.

Application

• Biomedical Research: Used as a reference standard and active agent in studies investigating the physiological and pathological roles of the apelinergic system.
• Receptor Binding Assays: Essential for competitive binding experiments to characterize the affinity and specificity of the APJ receptor.
• Signal Transduction Studies: Applied in cellular models to elucidate downstream signaling pathways activated by apelin peptide fragments.
• Drug Discovery & Development: Serves as a precursor or template for the design and screening of novel therapeutic agents targeting cardiovascular and metabolic diseases.
• In Vitro & In Vivo Pharmacology: Utilized in functional assays and animal models to evaluate the effects of apelin on blood pressure, heart function, and angiogenesis.
• Antibody Production & Immunoassays: Can be used as an immunogen for generating specific antibodies or as a calibrator in ELISA and other immunoassay formats.

Basic Information

Product Name	Apelin Precursor (61-77) (Human, Bovine, Mouse, Rat) Trifluoroacetate
CAS No.	217082-57-0
Molecular Formula	C86H134N24O23 • xC2HF3O2
Molecular Weight	~1887.1 g/mol (free base)
Synonyms	Apelin-36 (61-77); Pyr-apelin-13; Apelin (61-77); Apelin-17; Apelin-13 Precursor; [Pyr1]Apelin-13; Pyr1-apelin-13; L-Pyroglutamyl-apelin-13
EINECS	Contact for details

Quality Control

Our Apelin Precursor (61-77) Trifluoroacetate is manufactured under controlled conditions and undergoes rigorous analytical testing to ensure the highest standards of purity and identity for research applications. Each batch is supported by a comprehensive Certificate of Analysis (COA) detailing purity, peptide content, and impurity profiles. We adhere to stringent quality management protocols suitable for research and development use.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. This material is hygroscopic (moisture-sensitive). For long-term storage, keep desiccated. Allow the vial to equilibrate to room temperature before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to theoretical mass
Purity (HPLC)	≥95%
Peptide Content	≥70%
Water Content (KF)	≤8.0%
Acetate Content (HPLC)	≤10.0%
Single Impurity (HPLC)	≤2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.