Description

6-(4-Methoxy-Phenyl)-3-Pyridin-3-Yl-Pyrazolo[1,5-A]Pyrimidine is a high-purity, heterocyclic organic compound with the CAS registry number 216661-72-2. This specialized chemical serves as a critical advanced pharmaceutical intermediate and a versatile building block for medicinal chemistry research and development. It is primarily required by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for synthesizing novel active compounds.

Application

This compound is designed for advanced synthetic applications, particularly in the development of new therapeutic agents.

• Pharmaceutical Intermediate: A key building block in the synthesis of potential drug candidates targeting various diseases.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for novel small molecule therapies.
• Kinase Inhibitor Development: The pyrazolo[1,5-a]pyrimidine core is a privileged scaffold in the design of protein kinase inhibitors.
• Agrochemical Research: Serves as an intermediate in the development of new active ingredients for crop protection.
• Chemical Biology Probes: Utilized in the creation of molecular probes to study biological pathways and target validation.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs for the production of bespoke compounds and non-commercial scale-up.

Basic Information

Product Name	6-(4-Methoxy-Phenyl)-3-Pyridin-3-Yl-Pyrazolo[1,5-A]Pyrimidine
CAS No.	216661-72-2
Molecular Formula	C18H14N4O
Molecular Weight	302.33 g/mol
Synonyms	6-(4-Methoxyphenyl)-3-(pyridin-3-yl)pyrazolo[1,5-a]pyrimidine; 3-(3-Pyridinyl)-6-(4-methoxyphenyl)pyrazolo[1,5-a]pyrimidine; 216661-72-2; Pyrazolo[1,5-a]pyrimidine, 6-(4-methoxyphenyl)-3-(3-pyridinyl)-; 6-(4-Methoxy-phenyl)-3-pyridin-3-yl-pyrazolo[1,5-a]pyrimidine
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Every batch is characterized using advanced analytical techniques to guarantee identity, purity, and consistency. Certificates of Analysis (COA) detailing specific batch results are available upon request. We support development projects requiring material produced under GMP-like controls for non-clinical and early-phase clinical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (typically 15-25°C). For long-term storage, consider storing under an inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.