Description

Ethyl 1-(4,6-Dichloro-1,3,5-triazin-2-yl)piperidine-4-carboxylate is a high-value, functionalized heterocyclic building block featuring a reactive dichlorotriazine moiety. This compound is critical for researchers and manufacturers requiring precise molecular assembly, particularly in the synthesis of complex active pharmaceutical ingredients (APIs) and advanced agrochemicals. It is primarily sought after by the pharmaceutical, agrochemical, and specialty chemical industries for its role as a versatile linker and intermediate in medicinal chemistry and crop protection product development.

Application

• Pharmaceutical Intermediate: A key synthon in the development of novel small-molecule drugs, particularly those targeting central nervous system (CNS) disorders and infectious diseases.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides, where the triazine core contributes to biological activity.
• Bioconjugation & Linker Chemistry: The reactive dichlorotriazine group enables its use as a heterobifunctional cross-linking agent for attaching molecules to proteins, polymers, or surfaces in biotech applications.
• Material Science Research: Serves as a monomer or functional additive in the synthesis of specialty polymers and dendrimers with tailored properties.
• Chemical Biology Probes: Utilized in creating activity-based probes and affinity labels for studying enzyme function and protein interactions.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving global clients.

Basic Information

Item	Details
Product Name	Ethyl 1-(4,6-Dichloro-1,3,5-triazin-2-yl)piperidine-4-carboxylate
CAS No.	216502-45-3
Molecular Formula	C11H14Cl2N4O2
Molecular Weight	305.16 g/mol
Synonyms	Ethyl 1-(4,6-dichloro-1,3,5-triazin-2-yl)piperidine-4-carboxylate; 4,6-Dichloro-2-(4-(ethoxycarbonyl)piperidin-1-yl)-1,3,5-triazine; 2-(4-Carbethoxypiperidino)-4,6-dichloro-s-triazine; 1-(4,6-Dichloro-1,3,5-triazin-2-yl)-4-piperidinecarboxylic Acid Ethyl Ester; Ethyl 4-[(4,6-dichloro-1,3,5-triazin-2-yl)amino]piperidine-1-carboxylate (tautomer); 216502-45-3; 4,6-Dichloro-2-(4-ethoxycarbonylpiperidino)-1,3,5-triazine
EINECS	Contact for details

Quality Control

Our Ethyl 1-(4,6-Dichloro-1,3,5-triazin-2-yl)piperidine-4-carboxylate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment supports applications requiring GMP-grade intermediates and aligns with ICH guidelines for impurity profiling.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is moisture-sensitive (hygroscopic) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation. Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.