Description

Biotin Ethylenediamine is a high-purity, chemically modified derivative of biotin (Vitamin B7) designed for advanced pharmaceutical and biochemical applications. This compound is crucial for creating stable conjugates and probes due to its enhanced reactivity and specificity for avidin/streptavidin binding. It is primarily utilized by research institutions, diagnostic kit manufacturers, and pharmaceutical companies developing targeted therapies and advanced assay systems.

Application

• Pharmaceutical Intermediates: Serves as a key building block in the synthesis of targeted drug conjugates and novel biotinylated active pharmaceutical ingredients (APIs).
• Diagnostic Reagents: Used in the manufacture of ELISA kits, lateral flow assays, and other immunoassays where a stable biotin-streptavidin signal amplification system is required.
• Bioconjugation & Probe Development: Essential for labeling antibodies, proteins, and nucleic acids with biotin for detection, purification, and imaging applications in life science research.
• Cell Biology & Biochemistry: Employed in pull-down assays, affinity chromatography, and fluorescence-activated cell sorting (FACS) to study protein interactions and cellular processes.
• Nutraceutical & Cosmetic R&D: Investigated for potential use in advanced hair and skin care formulations due to its derivatized biotin structure.

Basic Information

Product Name	Biotin Ethylenediamine
CAS No.	216299-38-6
Molecular Formula	C12H22N4O2S
Molecular Weight	286.40 g/mol
Synonyms	Biotin-EDA; Biotin ethylenediamine conjugate; N-(2-Aminoethyl)-5-[(3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl]pentanamide; Biotinamidoethylamine; D-Biotinyl ethylenediamine; (+)-Biotinyl ethylenediamine; Vitamin B7 ethylenediamine derivative; Biotin-ethylenediamine adduct
EINECS	Contact for details

Quality Control

Our Biotin Ethylenediamine CAS NO 216299-38-6 is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and stringent tests for residual solvents and heavy metals. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to ensure traceability and compliance with your research or cGMP requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity. Allow the sealed container to reach room temperature before opening to prevent condensation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.