Description

A-Conotoxin Auib is a highly specific and potent peptide neurotoxin derived from the venom of marine cone snails. This compound is a valuable research-grade biochemical tool for studying nicotinic acetylcholine receptors (nAChRs) in neuroscience and pharmacology. It is primarily utilized by academic researchers, pharmaceutical R&D departments, and biotechnology companies for receptor characterization, neurological pathway mapping, and drug discovery programs.

Application

• Neuroscience Research: Selective probing and inhibition of specific subtypes of neuronal nicotinic acetylcholine receptors (nAChRs) to study synaptic transmission and neural circuitry.
• Pharmacological Studies: Used as a molecular tool to characterize receptor-ligand interactions, aiding in the understanding of receptor function and the development of novel therapeutic targets.
• Drug Discovery & Development: Serves as a lead compound or a template for designing new neuroactive drugs, particularly for conditions involving cholinergic systems.
• Biochemical Assay Development: Employed in the development and validation of high-throughput screening assays for identifying new nAChR modulators.
• Toxicology Research: Used to investigate the mechanisms of neurotoxicity and the physiological role of specific ion channels.

Basic Information

Product Name	A-Conotoxin Auib
CAS No.	216299-21-7
Molecular Formula	C58H86N18O18S5
Molecular Weight	1443.7 g/mol
Synonyms	α-Conotoxin AuIB; α-Conotoxin AuIB acetate; α-Conotoxin AuIB; Conotoxin α-AuIB; AuIB; α-AuIB; α-CTx AuIB; Acetylcholine receptor inhibitor α-AuIB
EINECS	Contact for details

Quality Control

Our A-Conotoxin Auib is produced under stringent conditions to ensure high purity and batch-to-batch consistency, suitable for sensitive research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and bioactivity. We adhere to rigorous internal quality standards to guarantee the integrity of this research biochemical. Certificates of Analysis (COA) are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. This product is hygroscopic (moisture-sensitive). For long-term storage, keep desiccated. Aliquot to avoid repeated freeze-thaw cycles.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 95%
Peptide Content	≥ 80%
Solubility	Soluble in water or aqueous buffers
Biological Activity	Verified by functional assay (e.g., nAChR inhibition)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.