Description

6 8-Difluoro-4-Methylumbelliferyl-β-& CAS NO 215868-26-1 is a specialized fluorogenic substrate and a key derivative of 4-methylumbelliferone. This compound matters for its enhanced sensitivity and specificity in enzymatic assays, particularly for β-glycosidase enzymes. It is primarily needed by researchers and manufacturers in the life sciences, diagnostics, and pharmaceutical development sectors for high-throughput screening and biochemical research.

Application

• Fluorogenic Substrate for Enzymology: Used as a sensitive probe for detecting and quantifying the activity of β-glucosidase, β-galactosidase, and related hydrolytic enzymes.
• Diagnostic Reagent Manufacturing: A critical component in the formulation of diagnostic kits for genetic disorders like Gaucher disease, where enzyme activity is a key biomarker.
• High-Throughput Screening (HTS): Employed in drug discovery platforms to identify potential inhibitors or activators of glycosidase enzymes.
• Biochemical Research: Serves as a tool for studying enzyme kinetics, mechanism of action, and substrate specificity in academic and industrial laboratories.
• Cell-Based Assays: Utilized in live-cell imaging and flow cytometry to monitor intracellular glycosidase activity.
• Microbiology: Applied in microbial identification systems that rely on specific enzymatic profiles.

Basic Information

Product Name	6 8-Difluoro-4-Methylumbelliferyl-β-& CAS NO 215868-26-1
CAS No.	215868-26-1
Molecular Formula	C₁₁H₈F₂O₅
Molecular Weight	258.18 g/mol
Synonyms	6,8-Difluoro-4-methylumbelliferyl β-D-glucopyranoside; 6,8-Difluoro-4-methylumbelliferyl-β-D-glucoside; 6,8-Difluoro-4-MU-β-D-glucoside; 4-Methylumbelliferyl-6,8-difluoro-β-D-glucopyranoside; 6,8-Difluoro-4-MUG; β-6,8-Difluoro-4-methylumbelliferylglucoside; 6,8-Difluoro-4-MU-β-Glc; 215868-26-1
EINECS	Contact for details

Quality Control

Our 6 8-Difluoro-4-Methylumbelliferyl-β-& CAS NO 215868-26-1 is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research and diagnostic applications. Certificates of Analysis (COA) with detailed specifications are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive) and light-sensitive (store away from light); desiccants are recommended for long-term storage. Keep away from strong acids and bases.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.