Description

(Ser79)-Proglucagon (78-107) Amide (Human, Bovine, Guinea Pig, Mouse, Rat) Trifluoroacetate Salt is a high-purity, synthetic peptide fragment of proglucagon, a key prohormone involved in glucose metabolism and appetite regulation. This specific, modified sequence is a critical research tool for studying the physiological roles and processing of glucagon-like peptides (GLPs) across multiple species. It is essential for pharmaceutical R&D, academic research, and diagnostic development focused on diabetes, obesity, and metabolic disorders.

Application

• Biomedical Research: Used as a reference standard and active agent in studies investigating proglucagon processing, GLP-1/GLP-2 biology, and islet cell function.
• Drug Discovery & Development: Serves as a key intermediate or analytical standard in the development of novel therapeutics targeting incretin pathways for diabetes and weight management.
• Immunoassay Development: Critical for the production and calibration of antibodies, ELISA kits, and other immunoassays designed to detect and quantify proglucagon-derived peptides.
• Metabolic Studies: Applied in in vitro and in vivo models to elucidate the mechanisms of glucose homeostasis, insulin secretion, and gut-brain signaling.
• Cross-Species Comparative Research: Enables comparative physiological studies across human, bovine, guinea pig, mouse, and rat models due to the provided sequence variants.
• Quality Control & Validation: Employed as a system suitability standard in analytical methods (e.g., HPLC, LC-MS) to ensure accuracy and reproducibility in peptide analysis.

Basic Information

Product Name	(Ser79)-Proglucagon (78-107) Amide (Human, Bovine, Guinea Pig, Mouse, Rat) Trifluoroacetate Salt
CAS No.	215777-46-1
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Proglucagon 78-107 Amide (Ser79); Glicentin-Related Pancreatic Peptide (GRPP); Oxyntomodulin (1-30); Proglucagon Fragment 78-107 Amide; TFA salt of Proglucagon (78-107) amide; Synthetic proglucagon peptide; GRPP (1-30); Research peptide 215777-46-1
EINECS	Contact for details

Quality Control

Our peptide products are manufactured and analyzed under strict quality management systems. Each batch of (Ser79)-Proglucagon (78-107) Amide Trifluoroacetate Salt undergoes comprehensive analytical testing, including HPLC for purity, MS for identity confirmation, and amino acid analysis. We provide a detailed Certificate of Analysis (COA) with each shipment, ensuring traceability and compliance with research-grade specifications. Custom synthesis and purification to meet specific purity requirements (e.g., >95%, >98%) are available.

Storage

Preserve in a tightly closed container, protected from light. Store desiccated at -20°C or below for long-term stability. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to prevent condensation and moisture uptake. For optimal stability, aliquot into single-use quantities to avoid repeated freeze-thaw cycles.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Retention time corresponds to reference standard
Identification (MS)	Mass spectrum consistent with theoretical molecular weight
Purity (HPLC)	≥95% (≥98% available)
Amino Acid Analysis	Composition within ±10% of theoretical
Peptide Content	≥80% (by weight)
Solubility	Soluble in water, acetic acid, or DMSO
Single Impurity (HPLC)	≤1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.