Description

1-[(Ammoniooxy)Methyl]-2-Fluorobenzene Chloride is a specialized fluorinated benzyl derivative with an oxyammonium functional group. This compound serves as a valuable building block and intermediate in advanced organic synthesis, particularly for introducing fluorinated motifs. It is primarily needed by pharmaceutical and agrochemical research and development teams for creating novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of fluorinated drug candidates, including potential CNS agents and enzyme inhibitors.
• Agrochemical Synthesis: Building block for developing new-generation herbicides, fungicides, and pesticides with enhanced activity and selectivity.
• Chemical Biology & Proteomics: Useful for modifying proteins or creating activity-based probes due to its reactive oxyammonium group.
• Material Science Research: Intermediate for synthesizing fluorinated monomers or ligands used in advanced polymers and catalysts.
• Cross-coupling Reactions: Serves as an electrophilic coupling partner in palladium-catalyzed reactions for biaryl formation.
• Radical Chemistry: Potential precursor for generating N-oxyl radicals used in oxidation processes and polymerization initiators.

Basic Information

Product Name	1-[(Ammoniooxy)Methyl]-2-Fluorobenzene Chloride
CAS No.	215599-91-0
Molecular Formula	C7H9ClFNO
Molecular Weight	177.60 g/mol
Synonyms	2-Fluorobenzyloxyammonium Chloride; (2-Fluorobenzyl)hydroxylammonium Chloride; N-Hydroxy-2-fluorobenzylaminium Chloride; 1-[(Ammoniooxy)Methyl]-2-Fluorobenzene Chloride; O-(2-Fluorobenzyl)hydroxylammonium Chloride; 2-Fluoro-α-(hydroxyamino)toluene Hydrochloride; α-(Hydroxyamino)-2-fluorotoluene Hydrochloride
EINECS	Contact for details

Quality Control

Our production of 1-[(Ammoniooxy)Methyl]-2-Fluorobenzene Chloride adheres to stringent internal quality standards to ensure batch-to-batch consistency and reliability for your synthetic workflows. Each lot is characterized by multiple analytical techniques, including NMR, HPLC, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment. We support cGMP compliance for advanced applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation. Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.