Description

4'-(Fmoc-Amino)-Biphenyl-4-Carboxylic Acid is a high-purity, protected amino acid derivative essential for solid-phase peptide synthesis (SPPS). This compound serves as a critical building block for the controlled introduction of biphenylalanine analogs into peptide chains, enabling the creation of complex biomolecules. It is primarily utilized by pharmaceutical researchers, CROs, and CDMOs engaged in the development of peptide-based therapeutics, diagnostics, and advanced materials.

Application

• Solid-Phase Peptide Synthesis (SPPS): A key Fmoc-protected intermediate for the incorporation of non-natural amino acids into peptide sequences.
• Pharmaceutical Research: Used in the discovery and development of novel peptide drugs, including hormone analogs and enzyme inhibitors.
• Chemical Biology: Serves as a building block for creating peptide probes and labeled biomolecules for studying protein-protein interactions.
• Material Science: A precursor for synthesizing specialized polymers and supramolecular structures with tailored properties.
• Combinatorial Chemistry: Employed in the generation of diverse peptide libraries for high-throughput screening.
• Bioconjugation: The carboxylic acid moiety allows for further functionalization and conjugation to other molecules or surfaces.

Basic Information

Product Name	4'-(Fmoc-Amino)-Biphenyl-4-Carboxylic Acid
CAS No.	215248-42-3
Molecular Formula	C27H21NO4
Molecular Weight	423.46 g/mol
Synonyms	Fmoc-4'-Amino-biphenyl-4-carboxylic Acid; 4'-(9-Fluorenylmethoxycarbonylamino)-[1,1'-biphenyl]-4-carboxylic Acid; N-[(1,1'-Biphenyl)-4'-yl]-N-(9-fluorenylmethoxycarbonyl)-4-carboxylic Acid; Fmoc-Biphenyl(4'-NH2)-4-COOH; Fmoc-4'-Ambi-4-COOH; N-Fmoc-4'-Aminobiphenyl-4-carboxylic Acid; 4'-(Fmoc-amino)-[1,1'-biphenyl]-4-carboxylic Acid
EINECS	Contact for details

Quality Control

Our 4'-(Fmoc-Amino)-Biphenyl-4-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical research and peptide synthesis. Certificates of Analysis (COA) with detailed chromatographic data are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.