Description

2-Amino-5-Hexynoic Acid is a specialized non-proteinogenic amino acid featuring a terminal alkyne functional group, making it a valuable bifunctional building block in synthetic chemistry. Its unique structure allows it to serve as a key intermediate for the synthesis of complex molecules and novel materials. This compound is particularly relevant for researchers and manufacturers in the pharmaceutical, agrochemical, and material science sectors who require advanced chiral intermediates for drug discovery, peptide mimetics, and click chemistry applications.

Application

• Pharmaceutical Intermediate: A crucial chiral synthon for the development of novel active pharmaceutical ingredients (APIs), especially in oncology and neurology research.
• Peptidomimetics & Conjugation: Used to incorporate alkyne handles into peptides and proteins for site-specific labeling, bioconjugation, and the development of peptide-based therapeutics.
• Click Chemistry Reagent: The terminal alkyne group enables efficient Huisgen 1,3-dipolar cycloaddition reactions with azides, facilitating the rapid assembly of diverse compound libraries and functional materials.
• Agrochemical Research: Serves as a building block for synthesizing novel herbicides, fungicides, and plant growth regulators with potentially improved efficacy.
• Material Science: Employed in the synthesis of functionalized polymers, dendrimers, and smart materials where precise molecular architecture is required.
• Chemical Biology Probes: Utilized to create activity-based probes and affinity tags for studying enzyme function and protein-protein interactions.

Basic Information

Product Name	2-Amino-5-Hexynoic Acid
CAS No.	215160-72-8
Molecular Formula	C6H9NO2
Molecular Weight	127.14 g/mol
Synonyms	5-Hexynoic acid, 2-amino-; 2-Aminohex-5-ynoic acid; (R/S)-2-Amino-5-hexynoic acid; DL-2-Amino-5-hexynoic acid; 2-Amino-5-hexynoate; Terminal alkyne amino acid; Hex-5-yn-2-aminic acid
EINECS	Contact for details

Quality Control

Our 2-Amino-5-Hexynoic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and chiral purity assessment, to ensure it meets the high standards required for research and development. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting identity, purity, and impurity profiles. We support compliance with relevant regulatory frameworks for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity	Contact for details
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.