Description

Amyloid β-Protein (1-6) CAS NO 214550-64-8 is a synthetic peptide fragment corresponding to the first six amino acids of the Amyloid-β protein, a key molecule in Alzheimer's disease research. This high-purity reference standard is critical for biochemical and pharmaceutical studies investigating the mechanisms of amyloid aggregation and neurotoxicity. It is primarily utilized by research institutions, diagnostic developers, and pharmaceutical companies engaged in neuroscience, biomarker discovery, and therapeutic development.

Application

• Biochemical Research: Used as a reference standard and substrate in studies of Amyloid-β protein aggregation kinetics and structure.
• Diagnostic Development: Serves as a critical antigen or calibrator in the development of immunoassays and biosensors for detecting amyloid-related biomarkers.
• Drug Discovery & Screening: Employed in high-throughput screening (HTS) assays to identify and validate potential inhibitors of amyloid peptide aggregation.
• Neuroscience Studies: Applied in cellular and animal models to investigate the pathophysiological role of amyloid fragments in neurodegenerative diseases.
• Antibody Production & Characterization: Acts as an immunogen for generating specific antibodies or as a ligand for testing antibody affinity and specificity.
• Quality Control: Used as a system suitability standard in analytical methods (e.g., HPLC, MS) for related peptide-based pharmaceuticals or research reagents.

Basic Information

Product Name	Amyloid β-Protein (1-6)
CAS No.	214550-64-8
Molecular Formula	C30H44N8O9
Molecular Weight	660.7 g/mol
Synonyms	DAEFRH; Aβ(1-6); Amyloid β-Protein (1-6); Amyloid β-Peptide (1-6); Asp-Ala-Glu-Phe-Arg-His; DAEFRH Peptide; β-Amyloid (1-6); Alzheimer's Disease Amyloid Peptide (1-6); Aβ1-6
EINECS	Contact for details

Quality Control

Our Amyloid β-Protein (1-6) is manufactured under strict quality systems to ensure batch-to-batch consistency and high purity, suitable for sensitive research applications. Each lot is characterized by advanced analytical techniques including HPLC and Mass Spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and peptide content is provided with every shipment to support your quality assurance and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dedicated freezer. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to prevent condensation and moisture uptake. For long-term storage, consider under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to theoretical mass
Purity (HPLC)	≥ 95%
Peptide Content	≥ 70% (by weight)
Amino Acid Analysis	Within ± 10% of theoretical
Solubility	Soluble in water or dilute aqueous acetic acid

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.