Description

Thanatin is a potent, naturally occurring antimicrobial peptide (AMP) known for its broad-spectrum activity against Gram-negative bacteria, fungi, and some enveloped viruses. Its unique mechanism of action, which involves disrupting the outer membrane of bacteria, makes it a compound of significant interest for overcoming antibiotic resistance. This makes it a critical material for researchers and developers in the pharmaceutical, biotechnology, and life science sectors focused on novel anti-infective therapies and preservative systems.

Application

• Antimicrobial Research: As a lead compound for developing new classes of antibiotics targeting multi-drug resistant (MDR) pathogens.
• Pharmaceutical Development: For formulation studies in topical antimicrobial creams, ointments, or wound healing products.
• Biotechnology & Life Sciences: Used in biochemical research to study peptide-membrane interactions and mechanisms of bacterial lysis.
• Preservative Systems: Exploration in high-value cosmetic or personal care formulations requiring natural or peptide-based preservatives.
• Veterinary Medicine: Research into novel treatments for bacterial infections in animals.
• Material Science: Investigation for creating antimicrobial surface coatings or functionalized biomaterials.

Basic Information

Product Name	Thanatin
CAS No.	214542-43-5
Molecular Formula	C95H139N31O25S2
Molecular Weight	2195.45 g/mol
Synonyms	Thanatin peptide; GSKKPVPIIYCNRRTGKCQRM; Antimicrobial peptide thanatin; Podisus maculiventris peptide; Insect-derived antimicrobial peptide; Antibacterial peptide TPN; Thanatin (1-21), disulfide bond: 11-18
EINECS	Contact for details

Quality Control

Our Thanatin is produced under stringent quality management systems to ensure batch-to-batch consistency and high purity for research and development applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We support compliance with relevant research and development standards, and specifications can be tailored to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below for long-term stability. This product is hygroscopic (moisture-sensitive); allow the vial to equilibrate to room temperature in a desiccator before opening to minimize moisture uptake. For short-term use, store at 2-8°C.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Peptide Content	≥ 80% (by weight)
Single Impurity (HPLC)	≤ 1.0%
Water Content (KF)	≤ 5.0%
Acetate Content (HPLC)	≤ 10.0%
Bacterial Endotoxins	< 10 EU/mg

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.