Description

4-Chloro-2-Phenylthieno[3,2-D]Pyrimidine is a high-value heterocyclic building block and key synthetic intermediate. This compound is critical for medicinal chemistry research and the development of novel pharmaceutical agents, particularly in kinase inhibitor programs. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced material sectors.

Application

• Pharmaceutical Intermediate: Serves as a core scaffold for the synthesis of potential kinase inhibitors targeting various disease pathways.
• Medicinal Chemistry Research: Used in hit-to-lead optimization and structure-activity relationship (SAR) studies due to its versatile functionalization points.
• Agrochemical Development: Acts as a precursor in the creation of new active ingredients for crop protection products.
• Chemical Biology Probe Synthesis: Employed to build molecular tools for studying biological processes and target validation.
• Material Science: Investigated as a building block for organic electronic materials and advanced polymers.
• Contract Research & Manufacturing (CRO/CMO): Supplied for custom synthesis and scale-up projects under cGMP or research-grade conditions.

Basic Information

Product Name	4-Chloro-2-Phenylthieno[3,2-D]Pyrimidine
CAS No.	214417-22-8
Molecular Formula	C12H7ClN2S
Molecular Weight	246.71 g/mol
Synonyms	4-Chloro-2-phenylthieno[3,2-d]pyrimidine; 2-Phenyl-4-chlorothieno[3,2-d]pyrimidine; Thieno[3,2-d]pyrimidine, 4-chloro-2-phenyl-; 4-Chloro-2-phenyl-thieno[3,2-d]pyrimidine; 214417-22-8; 4-Chloro-2-phenylthieno[3,2-d]pyrimidine; 4-Chloro-2-phenyl[1]benzothieno[3,2-d]pyrimidine (common misnomer); 4-Cl-2-Ph-thieno[3,2-d]pyrimidine
EINECS	Contact for details

Quality Control

Our 4-Chloro-2-Phenylthieno[3,2-D]Pyrimidine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and residual solvent analysis. Certificates of Analysis (COA) documenting identity, purity, and impurities are provided and can be tailored to meet specific project requirements, including ICH guidelines for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The compound is light-sensitive and should be handled under inert atmosphere for long-term storage to prevent degradation. Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Retention time corresponds to reference standard
Identification (NMR)	Spectrum consistent with structure
Purity (HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.