Description

2,6-Diiodo-4-(Trifluoromethyl)Aniline is a high-purity, multi-functional halogenated aniline derivative, serving as a critical building block in advanced organic synthesis. Its unique structure, featuring iodine and a trifluoromethyl group, makes it an indispensable intermediate for creating complex molecules with tailored electronic and steric properties. This compound is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly for targets requiring halogenated or fluorinated aromatic systems.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and pesticides where the iodine and trifluoromethyl groups enhance biological activity and environmental stability.
• Material Science Research: Serves as a monomer or functionalization agent in the creation of specialty polymers, liquid crystals, and organic electronic materials.
• Cross-Coupling Reactions: An excellent substrate for palladium-catalyzed reactions (e.g., Suzuki, Sonogashira) due to the reactivity of the iodine atoms, enabling the construction of complex biaryl structures.
• Fluorine Chemistry: Valuable for introducing the trifluoromethyl group into more complex molecules, a moiety highly prized in medicinal chemistry for its metabolic stability and lipophilicity.
• Chemical Reference Standard: Supplied as a high-purity standard for analytical method development and quality control in chemical manufacturing.

Basic Information

Product Name	2,6-Diiodo-4-(Trifluoromethyl)Aniline
CAS No.	214400-66-5
Molecular Formula	C7H4F3I2N
Molecular Weight	438.92 g/mol
Synonyms	4-Amino-3,5-diiodobenzotrifluoride; 2,6-Diiodo-4-(trifluoromethyl)benzenamine; 4-(Trifluoromethyl)-2,6-diiodoaniline; 3,5-Diiodo-4-(trifluoromethyl)aniline; 2,6-Diiodo-α,α,α-trifluoro-p-toluidine; Benzenamine, 2,6-diiodo-4-(trifluoromethyl)-; p-Toluidine, 2,6-diiodo-α,α,α-trifluoro-
EINECS	Contact for details

Quality Control

Our 2,6-Diiodo-4-(Trifluoromethyl)Aniline is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your research or production specifications. Our quality commitment supports applications requiring high-purity intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is light-sensitive and should be handled under an inert atmosphere when appropriate for prolonged use. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines
Water Content (KF)	< 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.