Description

5-Bromo-2-hydroxypyrimidine is a versatile halogenated pyrimidine derivative serving as a critical building block in advanced organic synthesis. Its value lies in its bifunctional reactivity, where the bromine atom facilitates cross-coupling reactions and the hydroxyl group allows for further functionalization. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and material science sectors, particularly for developing active pharmaceutical ingredients (APIs), novel crop protection agents, and specialty chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of nucleoside analogs, kinase inhibitors, and other small molecule therapeutics.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and plant growth regulators.
• Material Science Research: Serves as a monomer or functional unit in the creation of novel polymers, ligands, and organic electronic materials.
• Chemical Biology & Proteomics: Employed as a molecular scaffold or tagging reagent in probe development and bioconjugation.
• Cross-Coupling Reactions: The bromine substituent makes it a suitable substrate for Suzuki, Stille, and other palladium-catalyzed coupling reactions.
• Academic & R&D Laboratories: A fundamental reagent for methodological studies in heterocyclic and medicinal chemistry.

Basic Information

Product Name	5-Bromo-2-hydroxypyrimidine
CAS No.	214290-49-0
Molecular Formula	C4H3BrN2O
Molecular Weight	174.98 g/mol
Synonyms	5-Bromo-2(1H)-pyrimidinone; 5-Bromo-2-pyrimidinol; 2-Hydroxy-5-bromopyrimidine; 5-Bromopyrimidin-2-ol; 5-Bromo-2-hydroxypyrimidine; 5-Bromo-2-pyrimidinone; 5-Bromouracil (tautomer reference); 214290-49-0
EINECS	Contact for details

Quality Control

We supply 5-Bromo-2-hydroxypyrimidine in high-purity grades suitable for research and commercial synthesis. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request. We adhere to a cGMP-compliant quality management system to ensure batch-to-batch consistency and traceability.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound may be light-sensitive; prolonged exposure to light should be avoided.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Melting Point	Contact for details
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.