Description

2-Propenal,3-(2-Fluorophenyl)-,(2Z)-(9Ci) is a specialized fluorinated α,β-unsaturated aldehyde building block. This compound matters for its unique molecular architecture, which combines a reactive aldehyde group with a fluorinated aromatic system, enabling precise chemical modifications in advanced synthesis. It is primarily needed by researchers and process chemists in the pharmaceutical and agrochemical industries for the development of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of fluorinated drug candidates, particularly in kinase inhibitor and CNS-active molecule programs.
• Agrochemical Synthesis: Used in the creation of advanced herbicides and pesticides where the fluorine atom enhances biological activity and environmental stability.
• Material Science Research: Serves as a precursor for specialty polymers and liquid crystals, leveraging the fluorophenyl group to modify material properties.
• Chemical Biology Probes: Employed in the synthesis of fluorinated probes and tags for studying biological mechanisms and protein interactions.
• Cross-Coupling Reactions: Acts as an electrophilic partner in palladium-catalyzed cross-coupling reactions to construct complex biaryl systems.
• Asymmetric Synthesis: A valuable chiral building block for the preparation of enantiomerically pure compounds in medicinal chemistry.

Basic Information

Product Name	2-Propenal,3-(2-Fluorophenyl)-,(2Z)-(9Ci)
CAS No.	213617-46-0
Molecular Formula	C9H7FO
Molecular Weight	150.15 g/mol
Synonyms	(2Z)-3-(2-Fluorophenyl)prop-2-enal; (Z)-3-(2-Fluorophenyl)acrylaldehyde; 2-Fluorocinnamaldehyde (Z-isomer); (Z)-2-Fluorocinnamaldehyde; 3-(2-Fluorophenyl)-2-propenal, (Z)-; (Z)-3-(o-Fluorophenyl)acrylaldehyde; (2Z)-3-(2-Fluorophenyl)acrylaldehyde
EINECS	Contact for details

Quality Control

Our 2-Propenal,3-(2-Fluorophenyl)-,(2Z)-(9Ci) is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistent isomeric composition. Certificates of Analysis (COA) with detailed chromatographic data are provided to support your R&D and scale-up activities.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at controlled room temperature (15-25°C) in a cool, dry, and well-ventilated area. This material is easily oxidized and light-sensitive; prolonged exposure to air or light should be avoided to maintain stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Area %)
Isomeric Purity (Z-isomer)	≥ 95.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.