Description

L-β-Homoglutamine is a non-proteinogenic amino acid derivative, specifically a homologue of glutamine with an extended carbon chain. This structural modification makes it a valuable chiral building block and intermediate in advanced organic synthesis and pharmaceutical research. It is primarily utilized by research institutions and manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors for developing novel peptides, prodrugs, and bioactive compounds.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the research and development of new therapeutic agents, including peptide-based drugs and enzyme inhibitors.
• Biochemical Research: Used as a specialized substrate or analog in metabolic pathway studies and enzyme mechanism investigations.
• Peptide Synthesis: Serves as a building block for incorporating modified glutamine residues into synthetic peptides to alter their stability, bioavailability, or biological activity.
• Prodrug Design: Employed in the design of prodrugs to improve the pharmacokinetic properties of active pharmaceutical ingredients (APIs).
• Fine Chemical Synthesis: A versatile intermediate in the multi-step synthesis of complex organic molecules for various high-value applications.

Basic Information

Item	Details
Product Name	L-β-Homoglutamine
CAS No.	213487-90-2
Molecular Formula	C6H12N2O3
Molecular Weight	160.17 g/mol
Synonyms	(S)-2-Amino-5-carbamoylpentanoic acid; L-2-Amino-5-carbamoylvaleric acid; L-β-Homoglutamine; (S)-2,5-Diamino-5-oxopentanoic acid; β-Homo-L-glutamine; L-β-HGln; 2-Azaniumyl-5-carbamoylpentanoate
EINECS	Contact for details

Quality Control

Our L-β-Homoglutamine is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and chiral purity assessment, to ensure it meets high-grade specifications suitable for research and development. A Certificate of Analysis (COA) detailing identity, purity, and specific test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% (L-Isomer)
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.