Description

Ac-Dl-His-Oh H2O is a protected derivative of the amino acid histidine, specifically the acetylated form with a free carboxylic acid group, supplied as a monohydrate. This compound is a crucial building block in peptide synthesis and pharmaceutical research, offering a protected side chain that prevents unwanted reactions during complex molecular assembly. It is primarily utilized by research institutions, pharmaceutical developers, and fine chemical manufacturers engaged in the development of novel peptides, bioactive compounds, and advanced drug candidates.

Application

• Peptide Synthesis: Serves as a key protected intermediate in solid-phase and solution-phase peptide synthesis (SPPS).
• Pharmaceutical Research: Used in the research and development of peptide-based therapeutics and drug candidates.
• Biochemical Studies: Employed as a standard or reagent in studies involving histidine's role in enzyme catalysis and metal binding.
• Fine Chemical Production: Acts as a precursor for the synthesis of more complex, specialized organic molecules.
• Academic Research: Utilized in university and institutional labs for chemical biology and medicinal chemistry projects.

Basic Information

Product Name	Ac-Dl-His-Oh H2O
CAS No.	213178-97-3
Molecular Formula	C9H13N3O4 • H2O
Molecular Weight	245.23 g/mol (monohydrate)
Synonyms	N-Acetyl-DL-histidine; Acetyl-DL-histidine; Nα-Acetyl-DL-histidine; DL-2-Acetamido-3-(1H-imidazol-4-yl)propanoic acid monohydrate; NSC 76095; Ac-His-OH • H2O; N-Acetylhistidine (DL-form) monohydrate; (RS)-2-Acetamido-3-(1H-imidazol-5-yl)propanoic acid hydrate
EINECS	Contact for details

Quality Control

Our Ac-Dl-His-Oh H2O is produced under a strict quality management system to ensure batch-to-batch consistency and high purity suitable for research and development applications. Each lot undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation. A Certificate of Analysis (COA) detailing all test results is provided with every shipment to guarantee compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. Keep the container tightly sealed when not in use.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	6.0% - 8.5%
Optical Rotation	Contact for details
Heavy Metals	< 20 ppm
Residue on Ignition	< 0.2%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.