Description

(S)-2-((((9H-Fluoren-9-Yl)Methoxy)Carbonyl)Amino)-3-Aminopropanoic Acid Hydrochloride is a high-purity, protected amino acid derivative essential for solid-phase peptide synthesis (SPPS). Its core value lies in providing a precisely controlled chiral building block for the assembly of complex peptides and peptidomimetics. This product is critically needed by research institutions and pharmaceutical manufacturers developing therapeutic peptides, diagnostic agents, and biochemical tools.

Application

• Solid-Phase Peptide Synthesis (SPPS): As a key Fmoc-protected diaminopropionic acid (Dap) derivative for the sequential construction of peptide chains.
• Pharmaceutical Intermediate: For the research and production of peptide-based active pharmaceutical ingredients (APIs) and drug candidates.
• Bioconjugation: Serving as a linker or spacer molecule for attaching peptides to other biomolecules, surfaces, or labels.
• Combinatorial Chemistry: Used in libraries for high-throughput screening to discover new bioactive compounds.
• Biochemical Research: As a reagent for studying enzyme mechanisms, protein-protein interactions, and signal transduction pathways.
• Antibody-Drug Conjugate (ADC) Development: Potentially used in the synthesis of specialized linkers connecting cytotoxic drugs to antibodies.

Basic Information

Product Name	(S)-2-((((9H-Fluoren-9-Yl)Methoxy)Carbonyl)Amino)-3-Aminoproponic Acid Hydrochloride
CAS No.	212688-53-4
Molecular Formula	C18H18N2O4 • HCl
Molecular Weight	362.81 g/mol
Synonyms	Fmoc-Dap-OH • HCl; Fmoc-L-2,3-diaminopropionic acid hydrochloride; Nα-Fmoc-L-2,3-diaminopropanoic acid hydrochloride; (S)-2-(((9-Fluorenylmethoxy)carbonyl)amino)-3-aminopropanoic acid hydrochloride; Fmoc-L-Dap-OH • HCl; Nα-Fmoc-L-α,β-diaminopropionic acid HCl; Fmoc-2,3-diaminopropanoic acid hydrochloride; Fmoc-Dap(Mtt)-OH • HCl precursor
EINECS	Contact for details

Quality Control

Our (S)-2-((((9H-Fluoren-9-Yl)Methoxy)Carbonyl)Amino)-3-Aminopropanoic Acid Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and chiral integrity, to ensure compliance with exacting research and pharmaceutical-grade standards. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Optical Rotation	Contact for details
Water Content (KF)	≤1.0%
Heavy Metals	≤20 ppm
Residual Solvents	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.