Description

Fmoc-D-Ser(Trt)-Oh is a high-purity, protected amino acid derivative essential for solid-phase peptide synthesis (SPPS). This compound, with CAS number 212688-51-2, is a critical building block for the controlled assembly of complex peptides and proteins in research and development. It is primarily needed by pharmaceutical R&D laboratories, biotechnology companies, and academic institutions engaged in peptide-based drug discovery, proteomics, and biochemical studies.

Application

• Solid-Phase Peptide Synthesis (SPPS): A fundamental Fmoc-protected amino acid for the sequential construction of custom peptide sequences.
• Pharmaceutical Research: Used in the development and production of peptide therapeutics, hormones, and diagnostic agents.
• Combinatorial Chemistry: Serves as a key reagent in libraries for high-throughput screening of bioactive peptides.
• Bioconjugation: Acts as a precursor for introducing serine residues with orthogonal protecting groups for site-specific modifications.
• Academic & Institutional R&D: Employed in fundamental biochemical research to study protein structure, function, and interactions.
• Process Development: Used in scaling up and optimizing synthetic routes for peptide-based active pharmaceutical ingredients (APIs).

Basic Information

Product Name	Fmoc-D-Ser(Trt)-Oh
CAS No.	212688-51-2
Molecular Formula	C31H29NO5
Molecular Weight	495.57 g/mol
Synonyms	Fmoc-D-Serine(Trt)-OH; N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-O-trityl-D-serine; Fmoc-D-Ser(O-Trt)-OH; Fmoc-D-Ser(OTrt)-OH; (2R)-2-[(9H-Fluoren-9-ylmethoxy)carbonylamino]-3-oxo-3-(trityloxy)propanoic acid; D-Fmoc-serine-O-trityl; N-Fmoc-O-trityl-D-serine
EINECS	Contact for details

Quality Control

Our Fmoc-D-Ser(Trt)-Oh is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for sensitive research applications. Each lot undergoes comprehensive analytical testing, including HPLC for purity and chiral analysis to confirm enantiomeric integrity. Certificates of Analysis (COA) with detailed chromatographic data are provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Purity (HPLC)	≥98.0%
Optical Rotation	Contact for details
Water Content (KF)	≤1.0%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.