Description

Z-Ile-Ser-Oh is a protected dipeptide building block, specifically the Z-protected derivative of Isoleucine-Serine. This compound is a critical intermediate in the synthesis of complex peptides and peptidomimetics, offering precise control over stereochemistry and sequence. It is primarily utilized by research institutions and pharmaceutical companies engaged in drug discovery, process development, and the production of active pharmaceutical ingredients (APIs).

Application

• Solid-Phase Peptide Synthesis (SPPS): A key protected fragment for the sequential assembly of longer peptide chains.
• Solution-Phase Peptide Synthesis: Used in convergent synthesis strategies for larger or more complex peptide targets.
• Pharmaceutical Intermediate: Serves as a building block in the research and development of therapeutic peptides.
• Biochemical Research: Employed in studies of protein structure-function relationships and enzyme-substrate interactions.
• Peptidomimetic Design: Integral for creating modified peptide analogs with enhanced stability or biological activity.
• Custom Peptide Service: A fundamental component supplied to CROs and CDMOs for client-specific peptide manufacturing.

Basic Information

Product Name	Z-Ile-Ser-Oh
CAS No.	212612-25-4
Molecular Formula	C19H28N2O6
Molecular Weight	380.44 g/mol
Synonyms	Z-Isoleucyl-Serine; N-Cbz-Isoleucyl-Serine; Nα-Carbobenzoxy-L-isoleucyl-L-serine; Cbz-Ile-Ser-OH; Benzyloxycarbonyl-L-isoleucyl-L-serine; (2S,3S)-2-[[(2S)-2-[[(benzyloxy)carbonyl]amino]-3-methylpentanoyl]amino]-3-hydroxypropanoic acid; Z-L-Ile-L-Ser-OH; CBZ-ILE-SER
EINECS	Contact for details

Quality Control

Our Z-Ile-Ser-Oh is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis for enantiomeric excess, and identity confirmation via IR and NMR spectroscopy. Certificates of Analysis (COA) detailing all specifications are provided to ensure compliance with your research and cGMP-grade requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.