Description

3-Fluoro-5-Methylbenzyl Bromide is a versatile and reactive benzyl bromide derivative, serving as a critical building block in advanced organic synthesis. Its value lies in the strategic placement of fluorine and bromine substituents, which enable precise functionalization for creating complex molecular architectures. This high-purity intermediate is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and material science industries who require reliable, high-quality raw materials for their development and production processes.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds targeting the central nervous system or possessing specific receptor activity.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, where the fluorine atom can enhance biological activity and metabolic stability.
• Liquid Crystal & OLED Material Production: Serves as a building block for fluorinated organic electronic materials, contributing to improved performance in displays and lighting.
• Cross-Coupling Reactions: Employed in palladium-catalyzed reactions like Suzuki, Negishi, or Stille couplings to introduce the 3-fluoro-5-methylbenzyl moiety into more complex molecules.
• Ligand & Catalyst Development: Useful for synthesizing specialized ligands and organocatalysts used in asymmetric synthesis and other catalytic processes.
• Chemical Research & Development: A valuable reagent for medicinal chemistry and process chemistry teams exploring new chemical entities and optimizing synthetic routes.

Basic Information

Product Name	3-Fluoro-5-Methylbenzyl Bromide
CAS No.	212268-39-8
Molecular Formula	C8H8BrF
Molecular Weight	203.05 g/mol
Synonyms	1-(Bromomethyl)-3-fluoro-5-methylbenzene; (3-Fluoro-5-methylphenyl)methyl Bromide; α-Bromo-3-fluoro-5-methyltoluene; 3-Fluoro-5-methylbenzyl Bromide; 3-Fluoro-5-methylbenzylbromide; 3-Fluoro-5-methylbenzyl bromide; 3-Fluoro-5-methylbenzylbromide; 3-Fluoro-5-methylbenzyl bromide
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. We employ advanced analytical techniques including HPLC, GC, and NMR to verify identity, purity, and consistency for every batch. Certificates of Analysis (COA) are available upon request, providing full transparency and traceability to support your quality management systems and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic and moisture-sensitive nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen) to prevent degradation. Keep away from strong bases and incompatible materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.