Description

4-Chloro-2,3-Difluoro-6-Nitroaniline is a high-purity halogenated aniline derivative, serving as a critical building block in advanced organic synthesis. Its value lies in its unique substitution pattern, which enables the precise introduction of functional groups for creating complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing active ingredients and specialty fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), especially for fluorinated drug candidates targeting various therapeutic areas.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and pesticides, where the fluorine and chlorine atoms enhance biological activity and environmental stability.
• Dye and Pigment Manufacturing: Serves as a starting material for synthesizing specialized azo dyes and pigments with specific color fastness and performance properties.
• Material Science Research: Employed in the creation of advanced polymers, liquid crystals, and organic electronic materials due to its electron-withdrawing nitro and halogen groups.
• Cross-Coupling Reactions: Acts as a valuable substrate in palladium-catalyzed reactions (e.g., Buchwald-Hartwig amination) for constructing complex nitrogen-containing heterocycles.

Basic Information

Product Name	4-Chloro-2,3-Difluoro-6-Nitroaniline
CAS No.	211693-75-3
Molecular Formula	C6H3ClF2N2O2
Molecular Weight	208.55 g/mol
Synonyms	2,3-Difluoro-4-chloro-6-nitroaniline; 6-Amino-4-chloro-2,3-difluoronitrobenzene; 4-Chloro-2,3-difluoro-6-nitrobenzenamine; 1-Amino-4-chloro-2,3-difluoro-5-nitrobenzene; Benzenamine, 4-chloro-2,3-difluoro-6-nitro-; 211693-75-3; 4-Chloro-2,3-difluoro-6-nitro-phenylamine
EINECS	Contact for details

Quality Control

Our 4-Chloro-2,3-Difluoro-6-Nitroaniline is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity. Production adheres to cGMP guidelines where applicable, and each lot is supported by a comprehensive Certificate of Analysis (COA). The COA includes data from multiple analytical techniques such as HPLC, GC, NMR, and mass spectrometry to confirm identity, purity, and impurity profiles, meeting the stringent requirements of our global B2B clientele.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Due to its light-sensitive nature and tendency to be easily oxidized, it is recommended to store the material under an inert atmosphere (e.g., nitrogen or argon) for long-term stability. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.