Description

Interphotoreceptor Retinoid Binding Protein Fragment Irbp is a purified protein fragment derived from the Interphotoreceptor Retinoid-Binding Protein (IRBP), a critical component in the visual cycle. This high-purity biochemical is essential for advanced research into retinal physiology, photoreceptor function, and the molecular mechanisms of vision-related diseases. It serves as a key reagent for scientists and developers in ophthalmology research, diagnostic assay development, and pharmaceutical discovery targeting degenerative eye conditions.

Application

• Biomedical Research: Used as a critical antigen and standard in studies of autoimmune uveitis, retinal degeneration, and the visual retinoid cycle.
• Diagnostic Development: Serves as a coating antigen or calibrator in the development of immunoassays (ELISA) for detecting IRBP autoantibodies.
• Pharmaceutical Screening: Employed in high-throughput screening (HTS) platforms to identify potential therapeutic compounds that modulate IRBP function.
• Antibody Production: Acts as an immunogen for generating monoclonal or polyclonal antibodies specific to IRBP epitopes.
• Cell Culture & In Vitro Studies: Utilized in cell-based assays to study photoreceptor cell health, signaling, and response to oxidative stress.
• Reference Standard: Provides a characterized standard for quality control and validation in related biopharmaceutical processes.

Basic Information

Product Name	Interphotoreceptor Retinoid Binding Protein Fragment Irbp
CAS No.	211426-18-5
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	IRBP Fragment; Interphotoreceptor Retinoid-Binding Protein Peptide; Retinoid-Binding Protein Fragment; IRBP Antigen; IRBP Peptide; Autoantigen IRBP Fragment; Visual Cycle Protein Fragment
EINECS	Contact for details

Quality Control

Our Interphotoreceptor Retinoid Binding Protein Fragment Irbp is produced under stringent conditions to ensure batch-to-batch consistency and high biological activity. Each lot undergoes comprehensive analytical characterization, including purity assessment and functional validation. Certificates of Analysis (COA) detailing purity, identity, and biological activity are available upon request to support your regulatory and research documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below for long-term stability. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to prevent condensation and moisture uptake. For extended storage, consider under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Protein Content	≥ 90% (by weight)
Biological Activity	Confirmed by in vitro binding assay
Endotoxin Level	< 1.0 EU/mg
Solubility	Soluble in appropriate aqueous buffers

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.