Description

Benzyl 2-(4-Amino-2-Oxopyrimidin-1(2H)-Yl)Acetate CAS NO 211321-08-3 is a high-purity, protected nucleoside derivative primarily used as a critical building block in advanced pharmaceutical synthesis. This compound is essential for researchers and manufacturers developing novel antiviral and anticancer therapeutics, particularly in the field of nucleoside analog prodrugs. Its key value lies in providing a versatile, reactive intermediate that enables the precise construction of complex molecular architectures under controlled conditions. Target industries include pharmaceutical R&D, fine chemical synthesis, and biotechnology companies focused on innovative drug discovery programs.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of novel nucleoside analog prodrugs, particularly for antiviral and anticancer applications.
• Antiviral Drug Research: Serves as a crucial precursor in the development of next-generation therapeutics targeting viral polymerases and reverse transcriptases.
• Oncology Drug Discovery: Used in the construction of cytotoxic nucleoside analogs designed to inhibit cancer cell proliferation.
• Biochemical Research: Employed as a modified nucleoside base in studies of enzyme mechanisms, DNA/RNA interactions, and metabolic pathways.
• Fine Chemical Synthesis: Acts as a versatile building block for custom organic synthesis and the preparation of specialized chemical libraries.
• Prodrug Development: Utilized in designing masked nucleoside derivatives to improve drug bioavailability, targeting, and pharmacokinetic profiles.

Basic Information

Item	Detail
Product Name	Benzyl 2-(4-Amino-2-Oxopyrimidin-1(2H)-Yl)Acetate
CAS No.	211321-08-3
Molecular Formula	C₁₃H₁₃N₃O₃
Molecular Weight	259.26 g/mol
Synonyms	1-(Benzyloxycarbonylmethyl)cytosine; N4-Benzyloxycarbonyl Cytosine; Cbz-Cytosine; Benzyl N-(4-Amino-2-oxo-1,2-dihydropyrimidin-1-yl)acetate; 1-[(Benzyloxy)carbonylmethyl]cytosine; Cytosine, 1-(benzyloxycarbonylmethyl)-; 1-Carbobenzyloxymethylcytosine
EINECS	Contact for details

Quality Control

Every batch of Benzyl 2-(4-Amino-2-Oxopyrimidin-1(2H)-Yl)Acetate is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency meet the exacting standards required for pharmaceutical R&D and cGMP starting material applications. A comprehensive Certificate of Analysis (COA) detailing all test results and specifications is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed in a desiccated environment and away from direct light exposure to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.