Description

4-Chloro-7,8-Dimethoxyquinazoline is a high-purity, versatile quinazoline derivative that serves as a critical building block in advanced organic synthesis. This compound is valued for its reactive chloro substituent and methoxy functional groups, which enable precise molecular modifications. It is primarily sought after by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs) and specialty fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, particularly kinase inhibitors and other targeted therapeutics.
• Agrochemical Research: Used in the development of new herbicides and fungicides, leveraging the quinazoline core's bioactivity.
• Material Science: Serves as a monomer or functional unit in the creation of advanced organic electronic materials and liquid crystals.
• Academic & Contract Research: Employed in medicinal chemistry programs for structure-activity relationship (SAR) studies and library synthesis.
• Chemical Biology: Utilized as a probe or labeling agent in biochemical research due to its modifiable structure.

Basic Information

Product Name	4-Chloro-7,8-Dimethoxyquinazoline
CAS No.	211320-77-3
Molecular Formula	C₁₁H₁₀ClN₂O₂
Molecular Weight	238.66 g/mol
Synonyms	4-Chloro-7,8-dimethoxyquinazoline; 7,8-Dimethoxy-4-chloroquinazoline; 4-Chloro-7,8-bis(methoxy)quinazoline; Quinazoline, 4-chloro-7,8-dimethoxy-; 211320-77-3; 4-Chloro-7,8-dimethoxy-quinazoline
EINECS	Contact for details

Quality Control

Our 4-Chloro-7,8-Dimethoxyquinazoline is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets the stringent requirements of pharmaceutical R&D. A detailed Certificate of Analysis (COA) is provided with each shipment to guarantee traceability, consistency, and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.