Description

8-((1R,4S)-Bicyclo[2.2.1]Heptan-2-Yl)-2-(Methylthio)Pyrido[2,3-D]Pyrimidin-7(8H)-One is a high-purity, advanced pharmaceutical intermediate characterized by its complex, functionalized heterocyclic structure. This compound is of significant value in medicinal chemistry for its role as a key building block in the synthesis of novel therapeutic agents. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of small-molecule drugs targeting various disease pathways.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the multi-step synthesis of active pharmaceutical ingredients (APIs) for preclinical and clinical research.
• Medicinal Chemistry Research: Used as a scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Kinase Inhibitor Development: Its pyrido[2,3-d]pyrimidinone core is a privileged structure in the design of potent and selective kinase inhibitors for oncology and inflammatory diseases.
• Chemical Biology Probes: Employed in the creation of tool compounds for studying specific biological targets and signaling pathways.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations providing custom synthesis and process development services.
• Academic Research: Utilized in university and institutional labs for fundamental research in organic synthesis and heterocyclic chemistry.

Basic Information

Product Name	8-((1R,4S)-Bicyclo[2.2.1]Heptan-2-Yl)-2-(Methylthio)Pyrido[2,3-D]Pyrimidin-7(8H)-One
CAS No.	211246-27-4
Molecular Formula	C16H19N3OS
Molecular Weight	301.41 g/mol
Synonyms	8-[(1R,4S)-Bicyclo[2.2.1]heptan-2-yl]-2-(methylsulfanyl)pyrido[2,3-d]pyrimidin-7-one; 8-(1R,4S-Norborn-2-yl)-2-(methylthio)pyrido[2,3-d]pyrimidin-7(8H)-one; 2-(Methylthio)-8-((1R,4S)-norbornan-2-yl)pyrido[2,3-d]pyrimidin-7(8H)-one; (1R,4S)-2-(2-(Methylthio)-7-oxopyrido[2,3-d]pyrimidin-8(7H)-yl)norbornane; 211246-27-4; Pyrido[2,3-d]pyrimidin-7(8H)-one, 8-[(1R,4S)-bicyclo[2.2.1]hept-2-yl]-2-(methylthio)-
EINECS	Contact for details

Quality Control

Our 8-((1R,4S)-Bicyclo[2.2.1]Heptan-2-Yl)-2-(Methylthio)Pyrido[2,3-D]Pyrimidin-7(8H)-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical research. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept sealed in a desiccated environment and handled under appropriate conditions to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Any single impurity ≤ 1.0%
Total Impurities	≤ 3.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.