Description

L-Homoserine Methyl Ester is a high-purity chiral building block and protected amino acid derivative essential for advanced organic synthesis. This compound is valued for its role as a versatile intermediate in the production of complex pharmaceuticals, bioactive peptides, and fine chemicals. It is particularly critical for research and manufacturing in the pharmaceutical, biotechnology, and agrochemical sectors where precise stereochemistry and high purity are non-negotiable.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the synthesis of antibiotics, enzyme inhibitors, and other active pharmaceutical ingredients (APIs).
• Peptide Synthesis: Serves as a protected amino acid derivative in solid-phase and solution-phase peptide chemistry for research and therapeutic peptides.
• Bioconjugation & Probe Development: Used in the preparation of labeled compounds and molecular probes for biochemical and diagnostic applications.
• Agrochemical Research: Intermediate in the development of novel herbicides, fungicides, and plant growth regulators.
• Academic & Industrial R&D: A valuable reagent for methodological development in organic chemistry and asymmetric synthesis.
• Fine Chemical Production: Building block for synthesizing specialty chemicals with specific optical activity.

Basic Information

Product Name	L-Homoserine Methyl Ester
CAS No.	210772-73-9
Molecular Formula	C5H11NO3
Molecular Weight	133.15 g/mol
Synonyms	L-Homoserine, methyl ester; (S)-2-Amino-4-hydroxybutyric acid methyl ester; Methyl L-homoserinate; L-2-Amino-4-hydroxybutanoic acid methyl ester; H-Hse-OMe; (S)-Methyl 2-amino-4-hydroxybutanoate; Methyl (S)-2-amino-4-hydroxybutanoate
EINECS	Contact for details

Quality Control

Our L-Homoserine Methyl Ester is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. We provide comprehensive analytical documentation, including Certificates of Analysis (COA) with detailed HPLC/GC purity data, chiral purity (enantiomeric excess), and identification results. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (ee)	≥ 99.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.