Description

Boc-D-Asn(Trt)-OH is a high-purity, protected amino acid derivative essential for solid-phase peptide synthesis (SPPS). This compound is a critical building block for the controlled assembly of complex peptides and proteins, ensuring correct stereochemistry and side-chain protection. It is primarily utilized by pharmaceutical R&D teams, biotechnology companies, and CROs engaged in the development of therapeutic peptides, diagnostic agents, and biochemical research. Its reliable quality is fundamental for achieving high coupling efficiency and final product purity in advanced synthetic workflows.

Application

• Solid-Phase Peptide Synthesis (SPPS): A key intermediate for the sequential construction of custom peptide sequences.
• Pharmaceutical Research: Used in the development and scale-up of novel therapeutic peptide candidates, including hormone analogs and antimicrobial peptides.
• Bioconjugation: Serves as a protected precursor for incorporating D-Asparagine residues into protein conjugates or labeled biomolecules.
• Combinatorial Chemistry: Employed in libraries for drug discovery to explore structure-activity relationships (SAR).
• Biochemical Reagent Production: A raw material for synthesizing specialized reagents, enzyme substrates, and standards.
• Academic & Institutional Research: Fundamental tool for studies in organic chemistry, medicinal chemistry, and molecular biology.

Basic Information

Product Name	Boc-D-Asn(Trt)-OH
CAS No.	210529-01-4
Molecular Formula	C30H34N2O5
Molecular Weight	502.60 g/mol
Synonyms	Boc-D-Asparagine(Trt)-OH; (2R)-2-[(tert-Butoxycarbonyl)amino]-4-oxo-4-[(triphenylmethyl)amino]butanoic acid; Nα-Boc-Nγ-trityl-D-asparagine; Boc-D-Asn(Trt)-OH; tert-Butyloxycarbonyl-D-asparagine trityl ester; Boc-D-Asparagine(Trityl)-OH; N-tert-Butoxycarbonyl-N'-trityl-D-asparagine; D-Boc-Asn(Trt)-OH
EINECS	Contact for details

Quality Control

Our Boc-D-Asn(Trt)-OH is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for sensitive research and development applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to industry best practices, and our quality systems support compliance with relevant guidelines for advanced pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥98.0%
Optical Rotation	Contact for details
Water Content (KF)	≤1.0%
Heavy Metals	≤20 ppm
Residual Solvents	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.