Description

L-Phenylalanine, 3-[(1,1-Dimethylethoxy)Carbonyl]-n-[(9H-Fluoren-9-Ylmethoxy)Carbonyl]- is a protected amino acid derivative, specifically a Boc/Fmoc-protected L-phenylalanine analog, which is essential for solid-phase peptide synthesis (SPPS). This high-purity building block is critical for researchers and manufacturers requiring precise control over peptide chain assembly, ensuring high coupling efficiency and minimal racemization. It is primarily used by the pharmaceutical, biotechnology, and academic research sectors for developing therapeutic peptides, diagnostic agents, and novel bioactive compounds.

Application

• Solid-Phase Peptide Synthesis (SPPS): A key protected amino acid building block for the automated synthesis of complex peptides and proteins.
• Pharmaceutical Research & Development: Used in the discovery and production of peptide-based drugs, including hormones, antibiotics, and enzyme inhibitors.
• Bioconjugation and Labeling: Serves as a precursor for introducing the phenylalanine moiety into biomolecules for labeling or functionalization studies.
• Combinatorial Chemistry: Employed in libraries for high-throughput screening to identify new lead compounds with biological activity.
• Academic & Institutional Research: Fundamental reagent for studying protein structure-function relationships, peptide mimetics, and chemical biology.
• Process Development: Used in scaling up the production of therapeutic peptides under current Good Manufacturing Practice (cGMP) guidelines.

Basic Information

Product Name	L-Phenylalanine, 3-[(1,1-Dimethylethoxy)Carbonyl]-n-[(9H-Fluoren-9-Ylmethoxy)Carbonyl]-
CAS No.	210282-33-0
Molecular Formula	C29H29NO6
Molecular Weight	487.55 g/mol
Synonyms	Fmoc-Phe(3-Boc)-OH; N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-3-[(1,1-dimethylethoxy)carbonyl]-L-phenylalanine; Fmoc-3-(Boc)-L-phenylalanine; Boc-L-Phe(3-Fmoc)-OH; 3-(tert-Butoxycarbonyl)-N-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-phenylalanine; Fmoc-Phenylalanine(3-Boc); Protected L-Phenylalanine derivative; SPPS Amino Acid Building Block
EINECS	Contact for details

Quality Control

Our Boc/Fmoc-protected amino acids are manufactured under strict quality systems to ensure the high purity and consistency required for sensitive peptide synthesis. Each batch is characterized by advanced analytical techniques including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, chiral integrity, and impurity profiles is provided with every shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as specified on the label. This product is hygroscopic (moisture-sensitive); ensure the container is sealed under inert atmosphere after each use to maintain stability and prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥98.0%
Optical Rotation	[α]20/D: Specific range provided on COA
Water Content (KF)	≤0.5%
Heavy Metals	≤10 ppm
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.