Description

(6-Amino-1-Methyl-2-Thioxo-1,2-Dihydro-5-Pyrimidinyl)(Phenyl)Methanone is a high-purity, specialized heterocyclic building block of significant interest in advanced organic synthesis. This compound matters for its role as a key precursor in the development of novel pharmacologically active molecules, particularly within medicinal chemistry research. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Serves as a critical scaffold in the synthesis of potential drug candidates, particularly for kinase inhibitors and other targeted therapies.
• Medicinal Chemistry Research: Used extensively in hit-to-lead and lead optimization campaigns to explore structure-activity relationships (SAR).
• Agrochemical Development: Acts as a building block for creating novel active ingredients with herbicidal or pesticidal properties.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying enzyme function and biological pathways.
• Custom Synthesis & Contract Manufacturing: A valuable starting material for custom synthesis projects requiring complex pyrimidinone derivatives.
• Academic Research: Employed in university and institutional labs for methodological development and the discovery of new chemical reactions.

Basic Information

Product Name	(6-Amino-1-Methyl-2-Thioxo-1,2-Dihydro-5-Pyrimidinyl)(Phenyl)Methanone
CAS No.	210235-77-1
Molecular Formula	C12H11N3OS
Molecular Weight	245.30 g/mol
Synonyms	6-Amino-1-methyl-2-thioxo-1,2-dihydro-5-pyrimidinyl phenyl ketone; 6-Amino-1-methyl-2-thioxo-1,2,3,4-tetrahydropyrimidin-5-yl phenyl ketone; 5-Benzoyl-6-amino-1-methyl-2-thiouracil; (6-Amino-1-methyl-2-thioxo-1,2-dihydropyrimidin-5-yl)(phenyl)methanone; 5-Benzoyl-6-amino-1-methyl-2-thiouracil; Phenyl(6-amino-1-methyl-2-thioxo-1,2-dihydro-5-pyrimidinyl)methanone
EINECS	Contact for details

Quality Control

Our (6-Amino-1-Methyl-2-Thioxo-1,2-Dihydro-5-Pyrimidinyl)(Phenyl)Methanone is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure high consistency and reliability for your sensitive R&D and scale-up processes. Certificates of Analysis (COA) with detailed chromatographic data are provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.