Description

4-(Pyrimidin-4-Yl)Benzaldehyde is a high-purity aromatic aldehyde building block featuring a pyrimidine heterocycle, a structure of significant interest in advanced organic synthesis. This compound matters as a versatile and critical intermediate for constructing complex molecular architectures, particularly in the development of active pharmaceutical ingredients (APIs) and functional materials. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for creating novel compounds with targeted biological or physical properties.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of kinase inhibitors, receptor antagonists, and other small-molecule drug candidates targeting various therapeutic areas.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and plant growth regulators, leveraging the bioactivity of the pyrimidine moiety.
• Material Science: Serves as a building block for organic semiconductors, liquid crystals, and metal-organic frameworks (MOFs) due to its conjugated system and coordination sites.
• Chemical Biology: Employed in the design and synthesis of molecular probes, fluorescent tags, and PROTACs (Proteolysis Targeting Chimeras) for biological studies.
• Academic & Contract Research: Essential for methodological development and discovery chemistry in university and CRO (Contract Research Organization) laboratories.
• Scale-up & Process Chemistry: Suitable for optimization and kilogram-scale production under GMP or non-GMP conditions for clinical trial material supply.

Basic Information

Product Name	4-(Pyrimidin-4-Yl)Benzaldehyde
CAS No.	210115-39-2
Molecular Formula	C11H8N2O
Molecular Weight	184.20 g/mol
Synonyms	4-Pyrimidin-4-ylbenzaldehyde; 4-(4-Pyrimidinyl)benzaldehyde; 4-Formylphenylpyrimidine; Benzaldehyde, 4-(4-pyrimidinyl)-; p-(Pyrimidin-4-yl)benzaldehyde; 4-Pyrimidinylbenzaldehyde; 4-(4-Pyridinyl)benzaldehyde (related); Contact for details on additional trade names.
EINECS	Contact for details

Quality Control

Our 4-(Pyrimidin-4-Yl)Benzaldehyde is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment supports applications requiring high-purity intermediates, from research to commercial scale.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry place at 2-8°C for long-term stability. This compound is light-sensitive and easily oxidized; prolonged exposure to air, light, or ambient temperature may lead to degradation. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.