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3-Fluoro-4-(2-Methyl-1H-Imidazol-1-Yl)Aniline CAS NO 209960-27-0


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CAS No.:209960-27-0

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

3-Fluoro-4-(2-Methyl-1H-Imidazol-1-Yl)Aniline is a high-purity, functionalized aniline derivative featuring a fluorinated aromatic ring and a substituted imidazole moiety. This compound matters as a versatile and critical pharmaceutical intermediate for the synthesis of advanced active pharmaceutical ingredients (APIs), particularly in kinase inhibitor research. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to introduce specific fluorine and heterocyclic motifs into their target molecules.

Application

  • Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, especially kinase inhibitors and other targeted therapies.
  • Agrochemical Research: Used in the development of new herbicides and pesticides where the fluorine atom and imidazole ring can enhance biological activity and stability.
  • Material Science Precursor: Serves as a monomer or functionalizing agent for advanced polymers and organic electronic materials.
  • Chemical Biology Probes: Employed in the design of molecular probes and diagnostic agents due to its modifiable amine group and fluorinated aromatic system.
  • Organic Synthesis Reagent: Utilized in cross-coupling reactions and as a scaffold for constructing complex heterocyclic compounds in academic and industrial research.

Basic Information

Product Name 3-Fluoro-4-(2-Methyl-1H-Imidazol-1-Yl)Aniline
CAS No. 209960-27-0
Molecular Formula C10H10FN3
Molecular Weight 191.21 g/mol
Synonyms 1-(4-Amino-2-fluorophenyl)-2-methyl-1H-imidazole; 4-(2-Methyl-1H-imidazol-1-yl)-3-fluoroaniline; 3-Fluoro-4-(2-methylimidazol-1-yl)aniline; 2-Fluoro-4-amino-1-(2-methylimidazol-1-yl)benzene; Benzenamine, 3-fluoro-4-(2-methyl-1H-imidazol-1-yl)-; 209960-27-0; FC-IMP Intermediate
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Quality Control

Our 3-Fluoro-4-(2-Methyl-1H-Imidazol-1-Yl)Aniline is manufactured under a strict quality management system. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our production can adhere to cGMP guidelines for pharmaceutical applications upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is easily oxidized (store under inert atmosphere) and is light-sensitive (store away from light). Keep away from strong oxidizing agents.

Specification

Item Specification
Appearance White to off-white crystalline powder
Identification (IR) Conforms to structure
Identification (HPLC) Conforms to reference standard
Assay (HPLC) ≥98.0%
Related Substances (HPLC) Total impurities ≤2.0%
Water Content (KF) ≤0.5%
Residue on Ignition ≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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