Description

2'-Trifluoromethyl-Biphenyl-4-Ylamine is a high-purity aromatic amine derivative featuring a biphenyl core substituted with a trifluoromethyl group and an amine functionality. This compound is a critical pharmaceutical intermediate valued for its role in modulating the biological activity and pharmacokinetic properties of target molecules. It is primarily utilized by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides and fungicides, where the trifluoromethyl group enhances lipophilicity and metabolic stability.
• Material Science Research: Serves as a monomer or precursor in the development of specialty polymers, liquid crystals, and organic electronic materials.
• Chemical Research & Development: Employed as a versatile reagent in organic synthesis for constructing complex biphenyl-based structures in medicinal chemistry programs.

Basic Information

Product Name	2'-Trifluoromethyl-Biphenyl-4-Ylamine
CAS No.	209917-92-0
Molecular Formula	C13H10F3N
Molecular Weight	237.22 g/mol
Synonyms	[4-Aminophenyl](2-trifluoromethylphenyl)methane; 4'-Amino-2-(trifluoromethyl)biphenyl; 2-(Trifluoromethyl)-[1,1'-biphenyl]-4-amine; 2-Trifluoromethylbiphenyl-4-ylamine; Biphenyl-4-ylamine, 2'-trifluoromethyl-; 2'-Trifluoromethyl-4-aminobiphenyl
EINECS	Contact for details

Quality Control

Our 2'-Trifluoromethyl-Biphenyl-4-Ylamine is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and identity confirmation. We provide full traceability and Certificates of Analysis (COA) are available for all shipments to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.