Description

2(1H)-Pyrimidinethione, 5-(Trifluoromethyl)- (9Ci) is a high-value, heterocyclic organic compound featuring a pyrimidine core substituted with a thione group and a trifluoromethyl moiety. This unique structure makes it a critical building block and intermediate in advanced chemical synthesis, particularly valued for introducing the trifluoromethyl group which can dramatically alter a molecule's properties. It is primarily sought after by pharmaceutical and agrochemical research and development teams for creating novel active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, especially in antiviral, anticancer, and central nervous system (CNS) therapeutic areas.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, where the CF₃ group enhances biological activity and environmental stability.
• Material Science Research: Serves as a specialized monomer or additive in the development of advanced polymers and functional materials with specific electronic or surface properties.
• Organic Synthesis Building Block: Employed in cross-coupling reactions, nucleophilic substitutions, and other transformations to construct complex heterocyclic systems for research purposes.
• Ligand and Catalyst Development: Utilized in the preparation of novel ligands for metal catalysis or as a core structure in organocatalysts.

Basic Information

Product Name	2(1H)-Pyrimidinethione, 5-(Trifluoromethyl)- (9Ci)
CAS No.	209671-15-8
Molecular Formula	C₅H₃F₃N₂S
Molecular Weight	180.15 g/mol
Synonyms	5-(Trifluoromethyl)-2(1H)-pyrimidinethione; 5-(Trifluoromethyl)pyrimidine-2-thiol; 5-(Trifluoromethyl)-2-mercaptopyrimidine; 2-Mercapto-5-(trifluoromethyl)pyrimidine; 2-Thioxo-5-(trifluoromethyl)-1,2-dihydropyrimidine; 5-Trifluoromethyl-2-pyrimidinethiol; 209671-15-8
EINECS	Contact for details

Quality Control

Our 2(1H)-Pyrimidinethione, 5-(Trifluoromethyl)- (9Ci) is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure high purity and consistent identity. Certificates of Analysis (COA) with detailed specifications are provided for every shipment, supporting your R&D and scale-up activities with reliable data.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong oxidizing agents and strong bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.