Description

Ladostigil is a novel, multi-target neuroprotective agent with a unique pharmacological profile. This compound is of significant interest for its potential to address complex neurodegenerative pathologies through a single molecular entity. It is primarily utilized by pharmaceutical researchers and developers in the neuropharmacology and drug discovery sectors for preclinical and clinical studies.

Application

• Neuropharmacological Research: A key investigational compound for studying mechanisms of neuroprotection and cognitive enhancement.
• Drug Discovery & Development: Serves as a lead candidate or reference standard in the development of new therapies for neurodegenerative diseases.
• Preclinical Studies: Used in animal models to evaluate efficacy against conditions like Alzheimer's disease, Parkinson's disease, and depression.
• Mechanistic Studies: Employed to investigate the inhibition of monoamine oxidases (MAO-A and MAO-B) and cholinesterases.
• Clinical Trial Material (CTM): Supplied as a high-purity active pharmaceutical ingredient (API) for use in human clinical trials.
• Reference Standard: Used in analytical laboratories for method development, validation, and quality control of pharmaceutical products.

Basic Information

Product Name	Ladostigil
CAS No.	209394-27-4
Molecular Formula	C20H25N3O2
Molecular Weight	339.44 g/mol
Synonyms	TV-3326; (3aR)-N-Propargyl-3a,4,5,9b-tetrahydro-3H-benzo[g]indole-5-carboxamide; Ladostigil tartrate (salt form); TV3326; TV 3326; (3aR)-3a,4,5,9b-Tetrahydro-N-2-propyn-1-yl-3H-benzo[g]indole-5-carboxamide
EINECS	Contact for details

Quality Control

Our Ladostigil is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity, identity confirmation by spectroscopic methods, and stringent control of residual solvents and impurities. We provide full traceability and Certificates of Analysis (COA) are available for all shipments, ensuring compliance with research and development standards.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry environment. For long-term storage, consider storing under inert atmosphere to ensure maximum stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0%
Single Unknown Impurity	≤0.5%
Residual Solvents (GC)	Complies with ICH guidelines
Water Content (KF)	≤0.5%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.