Description

Finafloxacin Hydrochloride CAS NO 209342-41-6 is a synthetic fluoroquinolone antibiotic compound, representing a significant advancement in antimicrobial research due to its enhanced activity in acidic environments. This property makes it particularly valuable for targeting pathogens in challenging physiological conditions where other antibiotics may be less effective. It is primarily required by pharmaceutical R&D laboratories, contract manufacturing organizations (CMOs), and academic institutions engaged in developing novel antibacterial therapies for systemic and topical applications.

Application

• Pharmaceutical Active Ingredient (API) for the development of novel antibacterial drugs.
• Research Chemical for in-vitro and in-vivo studies on quinolone resistance mechanisms and efficacy.
• Preclinical Development of formulations targeting infections in low-pH environments, such as urinary tract infections (UTIs).
• Reference Standard for analytical method development and quality control in pharmaceutical manufacturing.
• Antimicrobial Susceptibility Testing (AST) to evaluate its spectrum against various Gram-positive and Gram-negative bacteria.
• Intermediate for the synthesis of more complex drug derivatives or prodrugs.

Basic Information

Product Name	Finafloxacin Hydrochloride
CAS No.	209342-41-6
Molecular Formula	C21H24F2N4O4 • HCl
Molecular Weight	470.90 g/mol
Synonyms	Finafloxacin HCl; (R)-7-[(3S,5R)-5-Amino-3-[(1-cyclopropyl-6-fluoro-8-methoxy-4-oxo-1,4-dihydroquinolin-3-yl)carbonyl]piperazin-1-yl]-1-cyclopropyl-6-fluoro-8-methoxy-4-oxo-1,4-dihydroquinoline-3-carboxylic acid hydrochloride; UNII-9K7J4VX8JN; Finafloxacin hydrochloride (JAN/USAN); Xtoro (brand name, for otic suspension); 8-Methoxy-fluoroquinolone antibiotic hydrochloride
EINECS	Contact for details

Quality Control

Our Finafloxacin Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency, meeting high standards for pharmaceutical research and development. Certificates of Analysis (COA) with detailed HPLC purity, related substances, and residual solvent data are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which can affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single unknown impurity ≤ 0.5%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.