Description

5-(Fmoc-Amino)-1-Pentanol is a high-purity, protected amino alcohol building block essential for solid-phase peptide synthesis (SPPS). Its core value lies in providing a versatile linker for the controlled introduction of functional groups or spacer arms into complex biomolecules. This compound is critically needed by researchers and manufacturers in the pharmaceutical and biotechnology sectors for developing novel peptide-based therapeutics, diagnostics, and research reagents.

Application

• Solid-Phase Peptide Synthesis (SPPS): Primary use as a versatile, Fmoc-protected linker for the stepwise assembly of peptides on resin.
• Bioconjugation & Labeling: Facilitates the attachment of peptides to other molecules, surfaces, or fluorophores via its hydroxyl and protected amine functionalities.
• Drug Discovery & Development: Serves as a key intermediate in the synthesis of peptide-drug conjugates (PDCs) and other targeted therapeutic agents.
• Material Science & Surface Modification: Used to create functionalized surfaces with bioactive peptides for tissue engineering, biosensors, and diagnostic arrays.
• Combinatorial Chemistry: A valuable building block for generating diverse libraries of peptide-like compounds for high-throughput screening.
• Antibody-Drug Conjugate (ADC) Research: Employed in the synthesis of specialized linkers that connect cytotoxic payloads to monoclonal antibodies.

Basic Information

Product Name	5-(Fmoc-Amino)-1-Pentanol
CAS No.	209115-33-3
Molecular Formula	C₂₀H₂₃NO₃
Molecular Weight	325.40 g/mol
Synonyms	1-Pentanol, 5-[[(9H-fluoren-9-ylmethoxy)carbonyl]amino]-; 5-[(Fmoc)amino]-1-pentanol; 5-(Fmoc-amino)pentan-1-ol; 5-Amino-1-pentanol, N-Fmoc-; Fmoc-5-amino-1-pentanol; N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-1,5-diaminopentane-5-ol; Fmoc-NH-(CH₂)₅-OH
EINECS	Contact for details

Quality Control

Our 5-(Fmoc-Amino)-1-Pentanol is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) detailing all specifications are provided with each shipment. We support development and production needs compliant with cGMP and ISO standards where required.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as indicated on the label or COA. This material is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.