Description

L-Homoserine, 3,3-Difluoro- (9Ci) is a high-purity, non-proteinogenic amino acid derivative featuring a difluoromethylene group, offering unique chemical and metabolic stability. This fluorinated building block is critical for advanced research and development in medicinal chemistry, enabling the synthesis of novel bioactive compounds. It is primarily sought by pharmaceutical R&D teams, agrochemical innovators, and academic researchers focused on creating new molecules with enhanced properties.

Application

• Pharmaceutical Intermediate: A key synthon for the development of fluorinated drug candidates, including protease inhibitors and enzyme modulators.
• Agrochemical Research: Used in the synthesis of novel, fluorinated amino acid-based herbicides and plant growth regulators.
• Peptide Chemistry: Incorporation into custom peptides to study the effects of fluorine substitution on structure, stability, and biological activity.
• Biochemical Probe Development: Serves as a stable, fluorine-labeled analog of homoserine for metabolic pathway studies and tracer applications.
• Material Science: Exploration as a monomer or precursor for specialty polymers and advanced materials.

Basic Information

Product Name	L-Homoserine, 3,3-Difluoro- (9Ci)
CAS No.	208756-00-7
Molecular Formula	C4H7F2NO3
Molecular Weight	155.10 g/mol
Synonyms	(2S)-2-Amino-4,4-difluorobutanoic acid; L-4,4-Difluorohomoserine; (S)-2-Amino-4,4-difluorobutanoic acid; 4,4-Difluoro-L-homoserine; L-3,3-Difluorohomoserine; (S)-4,4-Difluorohomoserine; 208756-00-7; L-α-Amino-γ,γ-difluorobutyric acid
EINECS	Contact for details

Quality Control

Every batch of L-Homoserine, 3,3-Difluoro- (9Ci) is produced and tested under strict quality management protocols. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for research and development. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is supplied with each shipment, confirming compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area. Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. Recommended long-term storage at 2-8°C.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Optical Purity (Chiral HPLC)	≥99.0% ee
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.