Description

4-Chloroquinazolin-6-Amine is a high-purity, synthetically valuable heterocyclic building block. This compound is essential for medicinal chemistry research and pharmaceutical development, serving as a key intermediate in the synthesis of targeted small molecule inhibitors. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries seeking to develop novel quinazoline-based active ingredients.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of kinase inhibitors and other targeted therapeutic agents.
• Medicinal Chemistry Research: Used as a scaffold for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.
• Agrochemical Development: Serves as a building block for creating novel herbicides, fungicides, and plant growth regulators.
• Fine Chemical Synthesis: Employed in the multi-step synthesis of complex, high-value specialty chemicals and dyes.
• Biochemical Tool Compound: Used to develop probes for studying enzymatic pathways and biological mechanisms.

Basic Information

Product Name	4-Chloroquinazolin-6-Amine
CAS No.	208533-37-3
Molecular Formula	C8H6ClN3
Molecular Weight	179.61 g/mol
Synonyms	6-Amino-4-chloroquinazoline; 4-Chloro-6-quinazolinamine; 4-Chloro-6-aminoquinazoline; 4-Chlor-6-chinazolinamin (German); 4-Chloro-quinazolin-6-ylamine; Quinazoline, 6-amino-4-chloro-; 208533-37-3 (CAS); 4-Cl-6-NH2-Quinazoline
EINECS	Contact for details

Quality Control

Our 4-Chloroquinazolin-6-Amine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with detailed chromatograms and spectral data are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.