Description

4-Chloro-5-Phenyl-7H-Pyrrolo[2,3-D]Pyrimidine is a high-value heterocyclic building block and pharmaceutical intermediate. This compound matters for its crucial role in the synthesis of complex molecules, particularly in medicinal chemistry for developing kinase inhibitors and other targeted therapeutics. It is primarily needed by research institutions, pharmaceutical R&D departments, and fine chemical manufacturers engaged in drug discovery and process development.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of novel kinase inhibitors and other small-molecule drug candidates.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.
• Biochemical Tool Compound: Serves as a precursor for developing labeled probes or active pharmaceutical ingredients (APIs) for biological testing.
• Fine Chemical Synthesis: Employed in multi-step organic synthesis to construct more complex nitrogen-containing heterocycles.
• Contract Research & Manufacturing (CRAM): Supplied to organizations offering custom synthesis and process development services.

Basic Information

Product Name	4-Chloro-5-Phenyl-7H-Pyrrolo[2,3-D]Pyrimidine
CAS No.	208459-81-8
Molecular Formula	C₁₂H₈ClN₃
Molecular Weight	229.66 g/mol
Synonyms	4-Chloro-5-phenyl-7H-pyrrolo[2,3-d]pyrimidine; 7H-Pyrrolo[2,3-d]pyrimidine, 4-chloro-5-phenyl-; 4-Chloro-5-phenyl-7H-pyrrolo[2,3-d]pyrimidine; 5-Phenyl-4-chloro-7H-pyrrolo[2,3-d]pyrimidine; 4-Chloro-5-phenyl-pyrrolo[2,3-d]pyrimidine; Pyrrolo[2,3-d]pyrimidine, 4-chloro-5-phenyl-7H-; 208459-81-8 (CAS)
EINECS	Contact for details

Quality Control

Our 4-Chloro-5-Phenyl-7H-Pyrrolo[2,3-D]Pyrimidine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR/LC-MS for identity confirmation, to ensure compliance with research and development grade standards. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.