Description

2-Fluoro-5-(Trifluoromethyl)Benzyl Alcohol is a versatile fluorinated aromatic building block of significant interest in advanced organic synthesis. Its value lies in the combination of a reactive benzyl alcohol group with fluorine and trifluoromethyl substituents, which are critical for modulating the physicochemical properties of target molecules. This compound is primarily needed by research and development chemists in the pharmaceutical and agrochemical industries for the creation of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly those targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the fluorine atoms enhance biological activity and environmental stability.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated components in electronic display materials and organic light-emitting diodes (OLEDs), improving performance and durability.
• Polymer & Resin Modifier: Incorporated into specialty polymers to impart unique properties such as chemical resistance, thermal stability, and altered surface energy.
• Cross-Coupling Reactions: The benzyl alcohol moiety can be transformed into various functional groups, making it a valuable substrate in Suzuki, Heck, and other palladium-catalyzed cross-coupling reactions.
• Fluorine Chemistry Research: An essential compound for academic and industrial research exploring new methodologies in fluorination and the synthesis of complex fluorinated architectures.

Basic Information

Product Name	2-Fluoro-5-(Trifluoromethyl)Benzyl Alcohol
CAS No.	207974-09-2
Molecular Formula	C8H6F4O
Molecular Weight	194.13 g/mol
Synonyms	[2-Fluoro-5-(trifluoromethyl)phenyl]methanol; α,α,α-Trifluoro-2-fluoro-5-tolylcarbinol; 2-Fluoro-α,α,α-trifluoro-m-tolylmethanol; (2-Fluoro-5-trifluoromethylphenyl)methanol; 1-(2-Fluoro-5-(trifluoromethyl)phenyl)methanol; 2-Fluoro-5-(trifluoromethyl)benzenemethanol; 5-(Trifluoromethyl)-2-fluorobenzyl alcohol
EINECS	Contact for details

Quality Control

Our 2-Fluoro-5-(Trifluoromethyl)Benzyl Alcohol is manufactured under a strict quality management system. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our production adheres to cGMP principles where applicable, ensuring reliability for research and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents and bases. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.