Description

Fmoc-Arg(Z)2-Oh CAS NO 207857-35-0 is a protected derivative of the amino acid arginine, featuring both Fmoc (9-fluorenylmethoxycarbonyl) and Z (benzyloxycarbonyl) protecting groups. This compound is a critical building block in solid-phase peptide synthesis (SPPS), enabling the controlled and sequential assembly of complex peptides. It is essential for researchers and manufacturers in the pharmaceutical and biotechnology sectors who require high-purity, protected amino acids for the development of peptide-based therapeutics, diagnostic agents, and research biochemicals.

Application

• Solid-Phase Peptide Synthesis (SPPS): A fundamental building block for the automated, sequential synthesis of peptides, particularly those containing arginine residues.
• Pharmaceutical Research & Development: Used in the discovery and production of peptide drugs, hormones, and vaccines where precise sequence control is paramount.
• Combinatorial Chemistry Libraries: A key reagent for generating diverse arrays of peptide compounds for high-throughput screening against biological targets.
• Bioconjugation & Protein Engineering: Facilitates the site-specific introduction of arginine or functional handles into larger biomolecules.
• Academic & Institutional Research: Supports fundamental studies in biochemistry, molecular biology, and medicinal chemistry involving peptide structure and function.
• Custom Peptide Service Providers: A staple raw material for CROs and CDMOs offering bespoke peptide synthesis services to the life science industry.

Basic Information

Product Name	Fmoc-Arg(Z)2-Oh
CAS No.	207857-35-0
Molecular Formula	C31H34N4O7
Molecular Weight	574.63 g/mol
Synonyms	Fmoc-Arg(Boc)2-OH (common alternate protection); Nα-Fmoc-Nω,ω'-bis(benzyloxycarbonyl)-L-arginine; Fmoc-NG,NG'-bis(Z)-L-arginine; Fmoc-Arg(Z2)-OH; (2S)-5-[(Benzyloxycarbonyl)amino]-2-(9H-fluoren-9-ylmethoxycarbonylamino)-N-(benzyloxycarbonyl)pentanamide; Fmoc-L-arginine(Z2)-OH; N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-Nω,ω'-bis[(benzyloxy)carbonyl]-L-arginine
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards for peptide synthesis. Each batch is characterized using advanced analytical techniques including HPLC, NMR, and mass spectrometry to confirm identity, purity, and chiral integrity. Certificates of Analysis (COA) detailing all test results are available upon request. We adhere to a quality management system to ensure batch-to-batch consistency and reliability for your critical research and production needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This material is hygroscopic (moisture-sensitive) and should be handled under dry conditions to maintain stability and purity. For long-term storage, consider storage under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Specific Rotation	Contact for details
Water Content (KF)	≤1.0%
Heavy Metals	≤20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.