Description

4-Nitro-L-Phenylalanine Monohydrate is a chiral, non-proteinogenic amino acid derivative where a nitro group is introduced at the para position of the phenyl ring. This functionalization makes it a valuable synthetic intermediate and building block in organic and medicinal chemistry. It is primarily utilized by research institutions and pharmaceutical companies for the development of novel compounds, including enzyme inhibitors and peptide-based therapeutics. The monohydrate form ensures stability for handling and storage.

Application

• Pharmaceutical Intermediate: Key chiral building block for synthesizing novel drug candidates and active pharmaceutical ingredients (APIs).
• Peptide Synthesis: Used to incorporate nitro-phenylalanine residues into custom peptides for biochemical research and drug discovery.
• Enzyme Inhibitor Development: Serves as a precursor for compounds designed to modulate enzyme activity in therapeutic pathways.
• Chemical Biology Probes: Employed in the creation of labeled or modified amino acids for studying protein structure and function.
• Organic Synthesis: Acts as a starting material or intermediate for complex organic molecules requiring a functionalized aromatic amino acid scaffold.
• Academic & Industrial Research: Fundamental reagent in R&D laboratories exploring new chemical entities and material science.

Basic Information

Product Name	4-Nitro-L-Phenylalanine Monohydrate
CAS No.	207591-86-4
Molecular Formula	C9H10N2O5 • H2O
Molecular Weight	244.20 g/mol (Anhydrous basis: 226.19 g/mol)
Synonyms	(S)-2-Amino-3-(4-nitrophenyl)propanoic acid monohydrate; L-4-Nitrophenylalanine monohydrate; p-Nitro-L-phenylalanine monohydrate; (S)-4-Nitrophenylalanine monohydrate; 4-Nitro-L-Phe-OH • H2O; 4-Nitro-L-Phenylalanine hydrate; 4-Nitro-L-α-aminohydrocinnamic acid monohydrate
EINECS	Contact for details

Quality Control

Our 4-Nitro-L-Phenylalanine Monohydrate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements for research and pharmaceutical development. Certificates of Analysis (COA) detailing purity, chiral purity, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	Yellow to pale yellow crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% (L-isomer)
Water Content (KF)	6.0 - 8.0%
Heavy Metals	≤ 20 ppm
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.