Description

2-Fluoro-3-(Trifluoromethyl)Phenol is a versatile fluorinated phenolic compound that serves as a critical building block in advanced chemical synthesis. Its unique structure, featuring both fluorine and trifluoromethyl substituents, imparts valuable properties such as enhanced lipophilicity and metabolic stability to target molecules. This high-purity intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of new drug candidates, especially in medicinal chemistry programs targeting kinase inhibitors and CNS-active compounds.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and pesticides, where the fluorine atoms contribute to biological activity and environmental persistence.
• Liquid Crystal Materials: Serves as a precursor in the synthesis of fluorinated liquid crystals for high-performance displays (LCDs).
• Polymer Modification: Acts as a monomer or additive to introduce fluorine functionality into polymers, enhancing their chemical resistance, thermal stability, and surface properties.
• Organic Synthesis Building Block: Employed in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and nucleophilic aromatic substitution to create complex, fluorinated aromatic systems.
• Material Science Research: Utilized in developing novel organic electronic materials, such as semiconductors for OLEDs and photovoltaic cells.

Basic Information

Product Name	2-Fluoro-3-(Trifluoromethyl)Phenol
CAS No.	207291-85-8
Molecular Formula	C7H4F4O
Molecular Weight	180.10 g/mol
Synonyms	2-Fluoro-3-(trifluoromethyl)phenol; 3-Trifluoromethyl-2-fluorophenol; 2-Fluoro-alpha,alpha,α-trifluoro-m-cresol; Phenol, 2-fluoro-3-(trifluoromethyl)-; 2-Fluoro-3-trifluoromethylphenol; o-Fluoro-m-trifluoromethylphenol; 2-Fluoro-3-(trifluoromethyl)hydroxybenzene
EINECS	Contact for details

Quality Control

Our 2-Fluoro-3-(Trifluoromethyl)Phenol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing purity, identity, and impurity profiles. Our quality commitment ensures the material meets the stringent requirements for research and cGMP-grade production applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be amber glass or opaque.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or crystalline solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.